Preview

Research Paper On Hemochromatosis

Better Essays
Open Document
Open Document
1152 Words
Grammar
Grammar
Plagiarism
Plagiarism
Writing
Writing
Score
Score
Research Paper On Hemochromatosis
Hemochromatosis
1 Hemochromatosis is a genetic metabolic disorder that affects over 1 million Americans 1. It is the result of the body absorbing too much iron 1. If the excess of iron continues to build up in the bloodstream it can cause damage to joints and organs, and can even be fatal 1.
Despite iron be harmful in this case, iron is an essential nutrient that is found in a daily diet. It is specifically responsible for carrying oxygen to all parts of the body. The normal absorption is 8 to 10 percent; however, in individuals with hemochromatosis this percentage can quadruple 1.
Hemochromatosis is one of the most common diseases in the United States and mainly affects Caucasians of Northern European ancestry 2. An estimated 4 to 5 out of
…show more content…
1 Classic Hemochromatosis, also known as type 1, is the leading cause of iron overload disease 1. People that are diagnosed with this type absorb too much iron from their diet 1. In result of the body not being able to get rid of the excess iron, the excess will build up in organs, such as the heart, liver, pancreas, joints, and pituitary 1. If the iron continues to stay in these organs, then it can cause them to become diseased and potentially be fatal 1. Another type is secondary hemochromatosis 2. Secondary hemochromatosis is not inherited and is caused by constant blood transfusions in people who have anemia 2. Additionally, liver diseases can cause a mild increase in iron levels 2. 2 The last type is neonatal hemochromatosis. Neonatal hemochromatosis is a rare disease that is distinguished by liver failure and death in fetuses and newborns 2. Researchers are trying to determine the cause of this specific type 2. Studies have found the mother’s immune system produces antibodies that cause damage to the fetus’ liver 2. Treating the women with intravenous immunoglobulin during pregnancy can prevent any potential liver damage to the fetus 2. Current research has determined that blood transfusions along with intravenous immunoglobulin is an efficient treatment for babies who are diagnosed with neonatal hemochromatosis

You May Also Find These Documents Helpful

  • Powerful Essays

    In chapter one it talks about how hemachromatosis is a hereditary disease and it’s the most common genetic disease for people of European descent, in which the body can't register that it has enough iron. So it keeps absorbing as much of it as possible, and this can have very, serious side effects (including death). Iron is very important for bacteria, cancer, and other things to grow. The way this disease is most easily treated is blood letting. Looks like all those crazy blood-letting, leech-sticking doctors weren't mistreating everyone. What is the author's argument for why this disease stuck around? To really simplify things: during the black plague in Europe, people with more iron in their system were more likely to die because bacteria feeds on iron. Women, children, and the elderly were less targeted than men. But people with hemachromatosis also happen to have white immune system blood cells with considerably less iron than the normal person, and this counteracted the precise way that the bubonic plague killed its victims - through their own immune system. Therefore, their immune system was actually able to fight off the bubonic plague, allowing them to live while 1/3 - 1/4 of the population died off. Even though hemachromatosis will eventually overload your system with iron, unabated, and cause you to die, it will save your life against normal infections. On the other hand, anemia has evolved because not having enough iron in your system means that it is hard for bacteria to live. While we do need iron, anemia has helped many populations avoid things like malaria.…

    • 1290 Words
    • 6 Pages
    Powerful Essays
  • Good Essays

    CaseStudy1Anemia

    • 817 Words
    • 3 Pages

    Anemia is the most common blood condition affecting over 3 million people in the United States. It is a medical condition where the red blood cell count or the hemoglobin count is below normal and there are no enough healthy red blood cells to carry adequate oxygen to the tissues. The normal level of hemoglobin in male and females are different. In men a hemoglobin level of less than 13.5 gram/100 ml is considered as anemia and in women hemoglobin of less than 12.0 gram/100 ml is considered as anemia. In the case study provided Ms. A appears to have Iron deficiency anemia based on her signs and symptoms. Iron deficiency anemia is a very common type of anemia affecting young women of reproductive age. It is a condition in which blood lacks adequate healthy red blood cells to carry oxygen to the tissues. Iron is considered to be very important in maintaining many body functions that includes the production of hemoglobin as well as to maintain the healthy cells, hair, skin and nails. Iron is absorbed into the body and is stored in the liver as ferritin and is released to the bone marrow to make new red blood cells. Risk factors of Iron deficiency Anemia- Women who menstruate and when their periods are heavy, people with gastrointestinal disorders when iron cannot be absorbed into the body, people who undergo bariatric surgeries etc. are some of the high risk group of people who may have iron deficiency anemia. In the case study Ms. A has heavy menstrual bleeding for almost ten to twelve years and she is also takes high doses of aspirin during her menstrual flow days (Harper, 2012). Signs and symptoms: The most common signs and symptoms of iron deficiency anemia are being pale, rapid heart rate, headaches, unexplained generalized weakness, fatigue and lack of energy, shortness of breath with activity,…

    • 817 Words
    • 3 Pages
    Good Essays
  • Good Essays

    Nsd 225 Study Guide

    • 2522 Words
    • 11 Pages

    13. Iron is VERY POORLY absorbed; only 5-10% of iron is absorbed by normal adults.…

    • 2522 Words
    • 11 Pages
    Good Essays
  • Satisfactory Essays

    Biology Lab 2

    • 432 Words
    • 2 Pages

    Our groups results seemed very conclusive. We rejected our null hypothesis and accepted our HA1 hypothesis. By the end of the simulation, only one non-restricted predator was able to survive. The restricted predators already knew that because they were restricted they had to move fast before their prey was stolen while the…

    • 432 Words
    • 2 Pages
    Satisfactory Essays
  • Better Essays

    MNT 1 Study Guide

    • 2089 Words
    • 11 Pages

    Iron Increasing foods vitamin C, empty stomach Serum Ferritin → stores the iron + present in the blood TIBC→ capacity of iron to bind to transferrin Transferrin → (transport protein) ↑during iron def. as body tries to transport more iron through body Diabetes ● HbA1C → glycosylation of glycation of hemoglobin in red blood cells ● Which of the following contributes to the dev.…

    • 2089 Words
    • 11 Pages
    Better Essays
  • Good Essays

    Absolute iron deficiency is when the stores of iron are depleted and bone marrow iron is absent, resulting in low serum ferritin and low transferrin saturation. Simple absolute iron deficiency usually results in iron deficiency anemia and can be resolved with iron supplementation. Functional iron deficiency results in anemia of chronic disease/inflammation, where infections, connective tissue disorders, or other diseases can cause inflammatory cytokines to be released. These inflammatory cytokines inhibit survival of erythroid progenitor cells, reduce EPO production, and cause excess hepcidin production, which decreases the amount of iron absorbed by enterocytes and blocks the release of iron stored in macrophages. In this case, the iron stores in the body are adequate, but are not being released for use, resulting in hypoferremia and creating a pathological basis for ACD.…

    • 855 Words
    • 3 Pages
    Good Essays
  • Good Essays

    Chem 8.06

    • 553 Words
    • 3 Pages

    -I chose genetic engineering/recombinant DNA technology/transgenesis of biotechnology to research and evaluate because that interests me the most, personally.…

    • 553 Words
    • 3 Pages
    Good Essays
  • Powerful Essays

    Ap Bio Diseases Research

    • 2176 Words
    • 9 Pages

    * Most common lethal genetic disease in the U.S, strikes one out of every 2,500 people of European descent.…

    • 2176 Words
    • 9 Pages
    Powerful Essays
  • Good Essays

    Throughout the novel, Moalem explains how certain hereditary diseases that are harmful to us and don’t make sense evolutionary are actually beneficial and were beneficial at a point in time. He begins by presenting us with a simple scenario that people might encounter everyday; taking pills. But he goes on to ultimately ask why would an individual take a pill that could kill them in forty years. And the answer was so that they don’t die tomorrow. To support this argument he talks about an inherited disease, hemochromatosis. Hemochromatosis is when our bodies absorb iron uncontrollably because it doesn’t think it has enough to the point where our joints hurt and become “rusted,” organs become…

    • 460 Words
    • 2 Pages
    Good Essays
  • Satisfactory Essays

    the stronger the gene/trait, the more likely is will adapt and be reproduced, vice versa…

    • 609 Words
    • 3 Pages
    Satisfactory Essays
  • Good Essays

    Hemophilia is the most common inherited coagulation disorder. Although hemophilia is commonly inherited, it can also occur due to a spontaneous mutation. Hemophilia A is an X-linked, recessive disorder caused by a deficiency of Factor VIII. Hemophilia can be severe, moderate, or mild. Individuals diagnosed with severe hemophilia A are typically diagnosed early in life, prior to age two. This is diagnosed particularly following episodes of bleeding from mouth injuries and bumps on the head. Spontaneous bleeding may occur as well as prolonged bleeding from injuries. Roughly five episodes of spontaneous or prolonged bleeding can occur each month. In cases of moderate hemophilia A, individuals have delayed clotting after minor injuries,…

    • 917 Words
    • 4 Pages
    Good Essays
  • Good Essays

    The Societal Machine

    • 937 Words
    • 4 Pages

    For decades, different groups of people have been subject to the oppressive nature of society, such as African Americans during the Civil Rights movement, or the same-sex couples of today’s day and age. Society is often a deterring factor to people’s dreams—it is no exception in the novel, One Flew Over the Cuckoo’s Nest by Ken Kesey. Narrator Chief Bromden refers to society as the Combine. The definition of a combine is “an agricultural machine that cuts, threshes, and cleans a grain crop in one operation,” or a machine that cuts and levels out that which it consumes. Society is like a combine in that it restrains, manipulates, and obliterates anyone who tries to stand up against it. Through his recount of the story of McMurphy and the other patients in the ward, Bromden shows that the Combine is able to control the patients by generating fear of authority and punishment in them, manipulating them by toying with these fears, and shutting down anyone who shows resistance.…

    • 937 Words
    • 4 Pages
    Good Essays
  • Better Essays

    Blood Disorders

    • 724 Words
    • 3 Pages

    Sickle cell is inherited and is normally only found in Black Americans. The blood cells are shaped differently and it due to a genetic defect. (WebMD, 2014) This causes the blood cells to eliminate themselves rather quickly causing lack of oxygen to the organs in the body. The reason this disease is so painful is because the blood cells become trapped in the blood vessels. (WebMD, 2014)…

    • 724 Words
    • 3 Pages
    Better Essays
  • Good Essays

    Circulatory Diseases

    • 300 Words
    • 2 Pages

    • Hemolytic Disease of the Newborn: A condition where the mother’s blood is incompatible with that of the fetus. The fetus may develop anemia and it could also be fatal.…

    • 300 Words
    • 2 Pages
    Good Essays
  • Better Essays

    Hemophilia B

    • 912 Words
    • 4 Pages

    a. Hemophilia A or factor VIII deficiency is the most common form of hemophilia and occurs in about 1 in every 10,000 males. A 2008 global survey by The World Federation of Hemophilia reported that there were about 12,000 people with hemophilia in the US and 108,000 worldwide.…

    • 912 Words
    • 4 Pages
    Better Essays