Sirsulin Type 2 Diabetes (SIRT1)

Diabetes is a chronic condition associated with abnormal high levels of sugar (glucose) in the blood. This condition is due to inadequate production of insulin, or because of the body's cells that do not respond properly to insulin, or both. Approximately 90% of all cases of diabetes worldwide are type 2 diabetes. It is a long-term metabolic disorder that is characterized by lack of sensitivity to insulin by the cells of the body. Sirtuin 1 (SIRT1), a NAD+-dependent histone deacetylase which regulates glucose/lipid metabolism through its deacetylase activity on many substrates. SIRT1 plays a major role in regulating insulin secretion and protects cells from oxidative stress and inflammation.SIRT1 also manages adiponectin secretion, inflammation,