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Steroid Rejection: A Case Study

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Steroid Rejection: A Case Study
Early treatment is essential as this greatly improves the chances of reversing the rejection process. Preservative-free topical steroids (dexamethasone phosphate 0.1% or prednisolone acetate 1%) given hourly for 24 hours are the mainstay of therapy. The frequency is reduced gradually over several weeks. Steroid ointment can be used at bedtime as the regimen is tapered. Single subconjunctival betamethasone (2 mg) or triamcinolone acetate (20 mg) injections have shown favorable results in terms of reversal of the rejection when combined with topical steroids (Costa et al., 2009). A single intravenous pulse of methylprednisolone (500 mg) was found to be more beneficial than oral prednisolone (1 mg/kg/day) in reversing rejection in patients who
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