A 17-year-old female with systemic lupus
A 17-year-old female was admitted with a month long history of involuntary movement bilaterally in hand and legs. The patient stated that the movement started one month ago. And she had occasionally involuntary movement of her mouth. The symptoms were mild in the beginning and gradually increased. The patient had dyskinesia around her mouth and thoracic and occasionally choreathetoid movement in bilateral upper extremity. She said she had similar movement in the lower extremity. The patient would not stand still and had difficulty while working.
She had consulted a rheumatologist about pain, swelling, redness in the joints, redness on the face and sensitivity to such sun light one and a half
month ago. After lab tests and physical examination the patient was diagnosed with systemic lupus and such was on methylprednisolone and hydroxylchoroquine for one month. The patient was diagnosed with central nervous system involvement of SLE and was hospitalised.
The patient’s cranial, cervical and thoracic MRI results were normal. Detailed lab tests were ordered to rule out the diagnosis other than SLE. The patient tested positive for anti-nuclear antibody (ANA) and Anti-rds. DNA that many cause movement disorders by affecting the central nervous system. The patient was positive for lupus, she responded very well to treatment on the movement disorder.
The patient was discharged and ant phospholipid antibody and ant ribosomal antibody. The neurological examination of the patient 3 months after the hospitalisation was normal. The patient had no signs of movement disorders, her olanzapine was discontinued. The neurological examination was normal in 2 weeks after the end of the treatment. The patient was still positive for lupus anticoagulant and ant ribosomal P antibody test, but she also tested positive for anticardiolipias antibodies and anti-B2 glycoprotein IIgM which were previously negative.