Taxol Research Paper
Medicines and Perturbation of Signaling Pathways- TAXOL
TAXOL (Paclitaxel) is a breast cancer curing drug which reduces, slows down the growth of cancerous cells and its spread in the human body. Taxol is a clear and colorless powder with the chemical formula- C47H51NO14 and a molecular weight of 853.9 g/mol. Taxol is also used to cure other types of cancer like ovarian, lung and prostate.
Taxol is a chemotherapeutic drug which mainly controls the growth of the cancerous cells. It belongs to the plant alkaloids class of chemo drugs, which are derived from the bark of the Pacific Yew tree. It is given in the form of an injection intravenously. It is not available in the form of a pill. The medication for Taxol is given by highly professional qualified doctors only because it is an irritant and if it is not given in a proper manner and proportion, it can cause tissue damage. There are severe allergic reactions that can occur to patients …show more content…
The HER2 has the potential to carry the cancerous cells in it. The HER2 gene is a 185-kD transmembrane glycoprotein which contains the cancerous cells, and the overexpression of it can cause major problems. It is overexpressed in 25-30% breast cancer issues and thus plays a vital role in the pathogenesis of breast cancer. To analyses the relationship between the effects of Taxol and the HER2 expression, a study was performed at Memorial Sloan-Kettering Cancer center. The HER2 expression was studied in 212 patients having metastatic breast cancer. The results showed that 35.5% of the patients responded to HER2 negative tumor while 65.2% to positive tumor. It was concluded that the patients with positive response to the tumor were supposed to respond to the Taxol drug while the negative response couldn’t respond to the drug. This proved that the Taxol drug has the ability to destroy the cancerous cells growing in the HER2
TAXOL (Paclitaxel) is a breast cancer curing drug which reduces, slows down the growth of cancerous cells and its spread in the human body. Taxol is a clear and colorless powder with the chemical formula- C47H51NO14 and a molecular weight of 853.9 g/mol. Taxol is also used to cure other types of cancer like ovarian, lung and prostate.
Taxol is a chemotherapeutic drug which mainly controls the growth of the cancerous cells. It belongs to the plant alkaloids class of chemo drugs, which are derived from the bark of the Pacific Yew tree. It is given in the form of an injection intravenously. It is not available in the form of a pill. The medication for Taxol is given by highly professional qualified doctors only because it is an irritant and if it is not given in a proper manner and proportion, it can cause tissue damage. There are severe allergic reactions that can occur to patients …show more content…
The HER2 has the potential to carry the cancerous cells in it. The HER2 gene is a 185-kD transmembrane glycoprotein which contains the cancerous cells, and the overexpression of it can cause major problems. It is overexpressed in 25-30% breast cancer issues and thus plays a vital role in the pathogenesis of breast cancer. To analyses the relationship between the effects of Taxol and the HER2 expression, a study was performed at Memorial Sloan-Kettering Cancer center. The HER2 expression was studied in 212 patients having metastatic breast cancer. The results showed that 35.5% of the patients responded to HER2 negative tumor while 65.2% to positive tumor. It was concluded that the patients with positive response to the tumor were supposed to respond to the Taxol drug while the negative response couldn’t respond to the drug. This proved that the Taxol drug has the ability to destroy the cancerous cells growing in the HER2