Preview

The Hot Zone

Good Essays
Open Document
Open Document
756 Words
Grammar
Grammar
Plagiarism
Plagiarism
Writing
Writing
Score
Score
The Hot Zone
Summary
Richard Preston’s Hot Zone is a horrific narration of the origin of filoviruses and their encounter with humans. These viruses include Marburg virus (MARV), Ebola virus (EBOV) and Sudan virus (SUDV). They are also known as Biosafety Level 4 agents because they are extremely dangerous to humans and have no treatments or cure.
Section 1: The Shadow of Mount Elgon This section details Charles Monet’s visit to Kitum cave, which is located in Mount Elgon, Kenya. During this trip, Monet is exposed to Marburg (MARV), a form of filovirus. Seven days after this exposure, Monet starts to suffer various symptoms of MARV such as headache and backache. He is rushed to Nairobi hospitals, where his internal organs fail while he is in the waiting room. He ends up bleeding and later in a coma.
Preston further describes the spread of MARV from Monet to Dr. Masoke. This happens when Monet vomits on Dr. Masoke, while Dr. Masoke is treating him. Preston points that the vomit is a sign of extreme amplification, which is a point when the host’s body becomes saturated with virus (Preston, 1994).
This section further introduces the reader to Dr. Nancy Jaax, who is employed in Level 4 Biosafety containment area at United States Army Medical Research Institute of Infectious Disease (USAMRIID). She has been assigned to research on Ebola virus. Preston points how Nancy first cuts her hand with a butcher knife while she is trying to open a can. Later, she is almost exposed to Ebola, through the open wound, while operating on a dead EBOV-infected monkey.
Preston also describes the emergence of some of the filoviruses such as the Ebola virus (EBOV) and Sudan virus (SUDV). For instance, he points that Ebola is named after the Ebola River located in Zaire. The first emergence of Ebola Zaire is known to have occurred in 1976 and it killed 9110 people. Furthermore, he points that MARV was named after a German City (Preston, 1994).
Apart from the emergence of these viruses,

You May Also Find These Documents Helpful

  • Good Essays

    This newly discovered strain of Ebola has researchers interested, but they’re approaching the facility with many safety precautions. For example, they were required to wear protective suits and were expected to take a ten minute break after every one hour of work inside of the faciliy. Nancy Jaax and her husband Jerry would constantly remind their young privates to be cautious, to amplify the severity of the situation. Even though this newly discovered Ebola strain isn't deadly to humans; Ebola's ability to transform and adjust to new environments strikes fear into researchers knowing there's a possibility of a potential mutation in the virus. The military's take over of the Reston Monkey house was predictable, yet necessary. Strict precautions needed to be enforced and the military was the best fit for a successful lock down of the Reston virus. The killing of the monkey's was sad, but the threat of spreading the virus proves necessary for this situation. This piece was significant to the book because it once again strengthens the severity of the situation, it scares the audience into believing that this is a life or death scenario with all of the prearranged precautions being followed through by the U.S. Military. This relates to the most recent outbreak because of the intensity, not only in safety protocols but the dedication to effectively remove the virus and…

    • 1479 Words
    • 6 Pages
    Good Essays
  • Satisfactory Essays

    5. Which is the worst of the filovirus “sisters”? What is the kill rate in humans?…

    • 643 Words
    • 5 Pages
    Satisfactory Essays
  • Good Essays

    During Project Ebola, two characters working in the USAMRIID are introduced, Nancy Jaax and Gene Johnson. Jaax is a very determined and strong-willed army veterinarian, she has a loving family consisting of her husband and two children. Johnson is a generally a timid person, he is an epidemiologist whose studies mainly focuses on Marburg and Ebola. They are both deeply terrified of Ebola, but are willing to risk their lives for a better understanding on the virus. On Nancy Jaax’s first day working in Biohazard Level 4, she puts on her space suit and Preston says, “Perhaps Nancy was in a bit of a hurry and did not inspect her spacesuit as closely as she should have.” (Preston 45). As for Johnson, Preston recalls his dreams as, “Gene Johnson had suffered recurrent nightmares about Ebola virus ever since he began to work with it.” (Preston 35). Both of these quotes suggest that a tragic incident shall soon unfold. These quotes are dark. These quotes give a feeling that cannot be shaken off, a prominent feeling of uncertainty and…

    • 525 Words
    • 3 Pages
    Good Essays
  • Good Essays

    Flaws of Contagion

    • 989 Words
    • 3 Pages

    In 2011, the blockbuster, Contagion, was released, featuring several prominent actors. In summary, the movie is the story of a father who loses his wife and son to a completely brand new virus. This new virus, dubbed MEV-1, originated from a bat in Hong Kong. The bat bit a fruit then dropped it into a pigpen infecting the pig that consumed the fruit with the bat’s virus. While pig was prepped to be cooked, the chef touched the pig’s mouth, getting virus on his hand and shakes the hands of woman, Beth, making her patient zero for MEV-1. The disease then spread to others who come in contact with Beth or Beth’s belongings. After the CDC realized the existence of this virus, they promptly started researching it. After several days of research, scientists were able to determine that the virus was “15 to 19 kilobases in length and containing six to ten genes, typical of a paramyxovirus” containing genes from bats and pigs, which attach to receptors found on cells in the respiratory and the central nervous system. The virus is seemingly able to be contracted through the respiratory tract, but kills the host by making its way to the brain and causing encephalitis. The vaccine for the virus was developed by first growing the virus in fetal bat cells in culture, propagating and isolating, and finally inoculating rhesus monkeys with attenuated and dead forms of the virus. Out of desperation for working vaccine, after observing one monkey surviving during the vaccination trials, one of the researchers injected herself with the tested vaccine given to the surviving chimp. By doing so, she skipped the entire clinical trials portion of developing vaccines and had the vaccine fastracked to be mass-produced.…

    • 989 Words
    • 3 Pages
    Good Essays
  • Good Essays

    Demon in the Freezer

    • 421 Words
    • 2 Pages

    Steven King's colossal works have been able to petrify people to their very core. In Preston's book, he has been able to clearly show reader's the history of the virus. If you…

    • 421 Words
    • 2 Pages
    Good Essays
  • Powerful Essays

    The Hot Zone

    • 9585 Words
    • 39 Pages

    Doctors at the hospital cannot explain Monet's illness, and their antibiotics have no effect, so they put him on a crowded plane to Nairobi Hospital. During the flight, Monet becomes so ill that he vomits huge amounts of blood with black specks. The author explains that this is vomito negro and that it is saturated with whatever virus is making Monet sick. His blood has been clotting in his blood vessels and internal organs, and by now his body has depleted the clotting agent. He is bleeding from his nose, as well as internally. By the time he reaches the hospital, Monet "crashes" and falls to the floor in a river of virus-infected blood.…

    • 9585 Words
    • 39 Pages
    Powerful Essays
  • Good Essays

    It was then that a secret military lab went to work to attempt to stop the spread and outbreaks of Ebola in its tracks. Lab specialist much like Nancy Jaax, set up an experiment where they observed the destruction of the Ebola virus through monkeys. This story is one that tells the traumatizing stories of the mysterious and deadly Ebola virus and its sudden appearance in the human race. It tells the stories of many people’s hopeless fight to survive against Ebola, while it ponders the origin of the hot agent that slowly destroys human existence.…

    • 1875 Words
    • 8 Pages
    Good Essays
  • Powerful Essays

    The Hot Zone Paper

    • 1704 Words
    • 7 Pages

    Within Richard Preston’s, The Hot Zone, the very real threats posed by the deadly viruses of Marburg and Ebola Reston is brought to attention through the “terrifying true story”. In the first chapter, Charles Monet is introduced as a man with a little too much free time and works at the pump house at the sugar factory within near the base of Mt. Elgon. One day in 1980, he takes a female friend to Kitum Cave, and it is believed that this is the day he caught the Marburg virus. The first symptoms include a severe headache; but, three days later, he starts vomiting. It is mentioned his eyes become red, and his face starts to droop. His skin changes color to yellow, and there are red specks all over his body. Once he is taken to the hospital, he eventually passes out by throwing up black vomit, that is described to have his bowels and parts of his intestines. The black vomit was the proof of extreme amplification within Monet, and once Dr. Musoke had a hold of him, he saw that blood came out of every opening of his body. Dr. Musoke tries to transfuse Monet’s blood, but every place in his arm where the needle was stuck, the vein broke apart like cooked macaroni and spilled blood. Monet officially dies, and when he is opened for an autopsy, they find that his kidneys and livers are destroyed - yellowed and parts of it liquified. Later however, when the USAMRIID inspects Kitum Cave, they find no evidence of the Marburg virus. Today, there is still relatively little we know about Marburg.…

    • 1704 Words
    • 7 Pages
    Powerful Essays
  • Good Essays

    The Hot Zone essay

    • 1755 Words
    • 8 Pages

    In the book the Hot Zone, by Richard Preston, the first few pages are introducing the reader into the world of contagious hot agents by going through the biosaftey procedures to access level 4. In part one, Charles Monet a fifty-six year old Frenchman living in western Kenya on the lands of the Nzoia Sugar Factory is introduced, but as his story continues he finds himself greatly ill by some unknown virus. It began shortly after a visit with a friend to Kitum Cave. Of course there’s no telling where exactly Monet really got the agent from, but where he got it probable wasn’t on his mind as it got worse.…

    • 1755 Words
    • 8 Pages
    Good Essays
  • Powerful Essays

    Hot Zone

    • 1423 Words
    • 6 Pages

    During this book, scientists at an Institute examine and test the virus to find out how it affects the human body. The first case infected with Marburg was a man named Charles Monet. He was a man who went to travel with his lady to Kitum Cave. While at the cave, he explores it and sees black-guano. Once he sees this he touches the guano and eventually gets sick. What Monet didn’t know was that he was infected with Marburg. When Monet’s vomit lands on the floor, he immediately gets admitted into the emergency room and is attended by Dr. Musoke. Then Dr. Musoke tried to open his airway by inserting a breathing tube in order for his lungs to get oxygen, and that is when Monet vomits. Black vomit comes out and this time lands in Dr. Musoke’s eyes. Monet goes into a deep coma and dies. The doctors never knew what Monet died of. The black vomit that Monet threw up in Dr. Musoke’s eyes was the virus’s way of getting from host to host. So the vomit that landed in his eyes was the virus’s home, but now Marburg would take Dr. Musoke as its host, and…

    • 1423 Words
    • 6 Pages
    Powerful Essays
  • Good Essays

    While reading “Diagnosis” it is explained that various employees that worked with the African green monkeys became ill after having contact with the contaminated subjects. Three victims that were mentioned were Klaus F., Heinrich P., and Renate L. These three individuals were exposed to either Infected materials, the habitat of the monkeys, or the killing of some of the contaminated monkeys. They fell ill and began showing symptoms seven days after being exposed like Monet and Dr. Musoke. This connection demonstrates how monkeys also carried the virus that would affect the slopes of Mount Elgon. The local chiefs explained that people “were suffering from a disease that caused bleeding, death, and “a peculiar skin rash” —and that monkeys in the area were dying of a similar disease.” (Preston, Pg. 58) Like some researchers I also believe that the African green monkeys could be carriers of the virus, however, I would like to confirm this as I keep reading the book any analyzing the information that is provided to…

    • 655 Words
    • 3 Pages
    Good Essays
  • Powerful Essays

    The Black Death

    • 1827 Words
    • 8 Pages

    This paper analyzes the documentary film "Secrets of the dead-Mystery of the Black Death". This film discusses about the Black Death, a disease resulting from a combination of bubonic and pneumonic plague, which killed millions of Europeans during the Middle Ages. Researchers in this video clarify the origins of this pandemic/how it spread, the damage it caused on the whole European continent, the theory explaining how some people managed to escape the Black Death and the relationship between the disease and today's most dangerous virus: the HIV. The team of experts in this film is composed of historians, geneticists, a microbiologist, a virologist and even a gastroenterologist. Thus, the combination of historical and scientific knowledge will answer the questions about the past that people have always asked.…

    • 1827 Words
    • 8 Pages
    Powerful Essays
  • Powerful Essays

    5. Filoviruses belong to a virus family called Filoviridae and there are two known types of viruses in this family: The Marburg and the Ebola.…

    • 1903 Words
    • 8 Pages
    Powerful Essays
  • Good Essays

    B. PLOT RELEVANCE: From this quote we can conclude that someone survived the accident. This led the scientists to have hope that there was a way to survive the virus even for a short period of time.…

    • 2609 Words
    • 11 Pages
    Good Essays
  • Powerful Essays

    DEVELOPMENT OF A WEB BASED RECRUITMENT PROCESS SYSTEM FOR THE HUMAN RESOURCE OF AN ORGANIZATION…

    • 1491 Words
    • 6 Pages
    Powerful Essays