Immune-mediated thrombocytopenia is likely identified with forms of neoplasia because the antibodies against tumor antigens may initiate the destruction of platelets. Common forms of neoplasia seen with thrombocytopenia include lymphoma, mast cell tumors, adenocarcinoma, and hemangiosarcoma. All causes of immune-mediated thrombocytopenia should be ruled out before considering a non-immune-mediated source of disease. Mechanisms that can cause non-immune mediated thrombocytopenia include hemorrhage, bone marrow suppression by radiation or chemotherapy, platelet consumption and others. Rare causes of thrombocytopenia include hemolytic uremia, inherited thrombocytopenia, and bone marrow
Immune-mediated thrombocytopenia is likely identified with forms of neoplasia because the antibodies against tumor antigens may initiate the destruction of platelets. Common forms of neoplasia seen with thrombocytopenia include lymphoma, mast cell tumors, adenocarcinoma, and hemangiosarcoma. All causes of immune-mediated thrombocytopenia should be ruled out before considering a non-immune-mediated source of disease. Mechanisms that can cause non-immune mediated thrombocytopenia include hemorrhage, bone marrow suppression by radiation or chemotherapy, platelet consumption and others. Rare causes of thrombocytopenia include hemolytic uremia, inherited thrombocytopenia, and bone marrow