Itp Research Paper
People try to live healthy life , but its become impossible sometimes. Lots of disorders happens to the human body and make trouble for people to get a healthy life. Some disorders make difficulties to lead normal life. ITP (Immune thrombocytopenic purpura) is a type of blood disorder that effect on people's normal life. It is a a platelet disorder in which the body produces antibodies that bind with platelets that are the small, sticky cells of the blood that help the blood clot.The platelet-antibody complex is then destroyed in the spleen or liver. This can occur as a short-term event or can be chronic. ITP affects women more frequently than men, and is more common in children than adults. The disease affects boys and girls equally. In children, the disease sometimes follows a viral infection. In adults, it is more often a chronic (long-term) disease and can occur after a viral infection, with use of certain drugs, during pregnancy, or as part of an immune disorder. ITP is related to an overactive immune
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system; however, the cause is not clearly understood. The condition happens more frequently following certain viral infections and certain immunizations. It also can be associated with autoimmune disorders such as lupus. Generally a child with ITP is otherwise healthy but has the sudden onset of bruises or small purple spots called petechiae on his/her skin. Spontaneous bleeding can occur in the mouth, nose, gastrointestinal tract or other areas. Bleeding can occur with injury and this can be especially dangerous if the bleeding occurs in the brain.
ITP effected people has this kind of symptoms.
There is no definitive, accurate test for ITP. The diagnosis of ITP involves assessing a medical history, physical examination and lab studies to be sure that the finding are consistent with ITP and that all other possible causes of the bleeding/bruising are ruled out. In most cases, a blood test, including a complete blood count and smear for morphology, are performed. Other blood tests that may be considered include autoimmune studies, viral labs, liver and renal function tests. A bone marrow test may be performed if there is a question as to the diagnosis. ITP in children resolves on its own. Your child's blood may be tested weekly or at longer intervals until the platelet count has returned to normal. Treatment may be recommended based upon the platelet count, age of the patient, activity level and bleeding symptoms.
The goal of treating ITP is to ensure a safe platelet count and prevent bleeding complications while minimizing treatment side effects. In children, idiopathic thrombocytopenic purpura usually runs its course without the need for treatment. About 80 percent of children with idiopathic thrombocytopenic purpura recover completely within six months. Even in children who develop chronic ITP, complete recovery may still occur, even years later. Adults with mild cases of ITP may require nothing more than regular monitoring and platelet checks. But if your symptoms are troublesome and your platelet count remains low, you and your doctor may opt for treatment. Treatment usually consists of medications and sometimes surgery (splenectomy). Your doctor may also have you discontinue certain drugs that can further inhibit platelet function, such as aspirin, ibuprofen (Advil, Motrin IB, others) and the blood-thinning medication warfarin (Coumadin). Common medications used to treat idiopathic thrombocytopenic purpura include: Corticosteroids, Intravenous immune globulin (IVIG), Thrombopoietin receptor agonists- Biologic therapy, Immunosuppressant drugs, H. pylori treatment. If someone has severe ITP and an initial course of prednisone hasn't helped, surgical removal of your spleen (splenectomy) may be an option. This quickly eliminates the main source of platelet destruction in your body and improves your platelet count, though it doesn't work for everyone. Splenectomy for ITP is not as routinely performed as it once was, however. Serious post-surgical complications sometimes occur, and not having a spleen permanently increases your susceptibility to infection. The patient or the parents of the patient have to be very carefull about this disorder.
Be aware of medications that may increase bleeding. Parents should check with the hematology team before giving your child any medication other than acetaminophen (Tylenol.)Keep your physician informed. If your child hits his/her head or has a serious accident, contact your hematologist immediately. Other signs or symptoms that should be noted and communicated to a physician include nosebleeds that last longer than 20 minutes, blood in the urine, stools, or vomit, blood during coughing. Be prepared to restrict activities when platelet counts are low. The hematology team will work with you to determine which sports and activities can continue and which pose a risk of bleeding that could be dangerous to a child with low platelet counts. Always make sure your child wears the appropriate safety equipment, such as helmets, kneepads, elbow pads, or wrist pads, during
sports. ITP ( idiopathic thrombocytic purpura) is a blood disorder that not only effect people physically but also effect them mentaly. Especially when a child has that disease it takes away the fun of childhood or enjoyable teenage from his/her life. May be sometimes they can do a little fun activities which is safe for them but still it tie a chain on their legs. Nowdays there is so many options for treatment, medication which help these patients to lead a normal life.
system; however, the cause is not clearly understood. The condition happens more frequently following certain viral infections and certain immunizations. It also can be associated with autoimmune disorders such as lupus. Generally a child with ITP is otherwise healthy but has the sudden onset of bruises or small purple spots called petechiae on his/her skin. Spontaneous bleeding can occur in the mouth, nose, gastrointestinal tract or other areas. Bleeding can occur with injury and this can be especially dangerous if the bleeding occurs in the brain.
ITP effected people has this kind of symptoms.
There is no definitive, accurate test for ITP. The diagnosis of ITP involves assessing a medical history, physical examination and lab studies to be sure that the finding are consistent with ITP and that all other possible causes of the bleeding/bruising are ruled out. In most cases, a blood test, including a complete blood count and smear for morphology, are performed. Other blood tests that may be considered include autoimmune studies, viral labs, liver and renal function tests. A bone marrow test may be performed if there is a question as to the diagnosis. ITP in children resolves on its own. Your child's blood may be tested weekly or at longer intervals until the platelet count has returned to normal. Treatment may be recommended based upon the platelet count, age of the patient, activity level and bleeding symptoms.
The goal of treating ITP is to ensure a safe platelet count and prevent bleeding complications while minimizing treatment side effects. In children, idiopathic thrombocytopenic purpura usually runs its course without the need for treatment. About 80 percent of children with idiopathic thrombocytopenic purpura recover completely within six months. Even in children who develop chronic ITP, complete recovery may still occur, even years later. Adults with mild cases of ITP may require nothing more than regular monitoring and platelet checks. But if your symptoms are troublesome and your platelet count remains low, you and your doctor may opt for treatment. Treatment usually consists of medications and sometimes surgery (splenectomy). Your doctor may also have you discontinue certain drugs that can further inhibit platelet function, such as aspirin, ibuprofen (Advil, Motrin IB, others) and the blood-thinning medication warfarin (Coumadin). Common medications used to treat idiopathic thrombocytopenic purpura include: Corticosteroids, Intravenous immune globulin (IVIG), Thrombopoietin receptor agonists- Biologic therapy, Immunosuppressant drugs, H. pylori treatment. If someone has severe ITP and an initial course of prednisone hasn't helped, surgical removal of your spleen (splenectomy) may be an option. This quickly eliminates the main source of platelet destruction in your body and improves your platelet count, though it doesn't work for everyone. Splenectomy for ITP is not as routinely performed as it once was, however. Serious post-surgical complications sometimes occur, and not having a spleen permanently increases your susceptibility to infection. The patient or the parents of the patient have to be very carefull about this disorder.
Be aware of medications that may increase bleeding. Parents should check with the hematology team before giving your child any medication other than acetaminophen (Tylenol.)Keep your physician informed. If your child hits his/her head or has a serious accident, contact your hematologist immediately. Other signs or symptoms that should be noted and communicated to a physician include nosebleeds that last longer than 20 minutes, blood in the urine, stools, or vomit, blood during coughing. Be prepared to restrict activities when platelet counts are low. The hematology team will work with you to determine which sports and activities can continue and which pose a risk of bleeding that could be dangerous to a child with low platelet counts. Always make sure your child wears the appropriate safety equipment, such as helmets, kneepads, elbow pads, or wrist pads, during
sports. ITP ( idiopathic thrombocytic purpura) is a blood disorder that not only effect people physically but also effect them mentaly. Especially when a child has that disease it takes away the fun of childhood or enjoyable teenage from his/her life. May be sometimes they can do a little fun activities which is safe for them but still it tie a chain on their legs. Nowdays there is so many options for treatment, medication which help these patients to lead a normal life.