anatomy and physiology

PHYSIOEX 9.0
REVIEW SHEET
EXERCISE 4
Endocrine System Physiology
NAME ___
LAB TIME/DATE ___
ACTIVITY 1 Metabolism and Thyroid Hormone
Part 1
1 Which rat had the fastest basal metabolic rate (BMR)? ___
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2 Why did the metabolic rates differ between the normal rat and the surgically altered rats? How well did the results compare with your prediction? ___
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3 If an animal has been thyroidectomized, what hormone(s) would be missing in its blood? ___
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4 If an animal has been hypophysectomized, what effect would you expect to see in the hormone levels in its body? ___
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Part 2
5 What was the effect of thyroxine injections on the normal rat’s BMR? ___
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6 What was the effect of thyroxine injections on the thyroidectomized rat’s BMR? How does the BMR in this case compare with the normal rat’s BMR? Was the dose of thyroxine in the syringe too large, too small, or just right? ___
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7 What was the effect of thyroxine injections on the hypophysectomized rat’s BMR? How does the BMR in this case compare with the normal rat’s BMR? Was the dose of thyroxine in the syringe too large, too small, or just right? ___
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Part 3
8 What was the effect of thyroid-stimulating hormone (TSH) injections on the normal rat’s BMR? ___
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9 What was the effect of TSH injections on the thyroidectomized rat’s BMR? How does the BMR in this case compare with the normal rat’s BMR? Why was this effect observed? ___
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10 What was the effect of TSH injections on the hypophysectomized rat’s BMR? How does the BMR in this case compare with the normal rat’s BMR? Was the dose of TSH in the syringe too large, too small, or just right? ___
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Part 4
1. What was the effect of propylthiouracil (PTU) injections on the normal rat’s BMR? Why did this rat develop a palpable goiter?
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2. What was the effect of PTU injections on the thyroidectomized rat’s BMR? How does the BMR in this case compare with the normal rat’s BMR? Why