Roadmap Clinical problems
CLINICAL PROBLEMS
A 26-year-old woman comes to an allergy clinic complaining of a runny nose and itching eyes. The symptoms become particularly severe during the spring months. She has tried over-the-counter antihistamines and they help reduce the symptoms, but also cause side effects that she finds intolerable. 1. Which of the following drugs would you not recommend?
A. Cetirizine
B. Desloratadine
C. Diphenhydramine
D. Fexofenadine E. Loratadine
A 45-year-old man is to undergo chemotherapy for a testicular tumor.
2. Which of the following drugs is most likely to be used concomitantly as an antiemetic?
A. Bromocriptine
B. Ergotamine
C. Ibuprofen
D. Ondansetron
E. Sumatriptan
A 63-year-old man has glaucoma and requires treatment to lower the intraocular pressure.
3. Which of the following eicosanoids is most likely to be used?
A. Alprostadil
B. Dinoprostone
C. Latanoprost
D. Misoprostol
E. Prostacyclin
A 65-year-old woman comes to your office with a complaint of black stools and “feeling weak.” Stool testing for occult blood is strongly positive and her hemoglobin is 8 g/ dL (normal 12– 14 g/ dL). Medical history reveals that she has had rheumatoid arthritis for 15 years. On a doctor’s recommendation, she has treated her symptoms with aspirin with good control of her symptoms. Your diagnosis is gastrointestinal bleeding due to the NSAID.
4. Which of the following drugs will control her rheumatoid arthritis symptoms with the smallest risk of bleeding?
A. Diclofenac
B. Ibuprofen
C. Ketorolac
D. Naproxen
E. Valdecoxib
A 57-year-old man has been found in a screening program to have elevated total cholesterol (285 mg/ dL, desirable < 200 mg/ dL) and elevated triglycerides. He has a family history of early cardiovascular disease. 5. Which of the following drugs should not be used in his treatment?
A. Atorvastatin
B. Colestipol
C. Gemfibrozil
D. Lovastatin
E. Niacin
ANSWERS 1. The answer
A 26-year-old woman comes to an allergy clinic complaining of a runny nose and itching eyes. The symptoms become particularly severe during the spring months. She has tried over-the-counter antihistamines and they help reduce the symptoms, but also cause side effects that she finds intolerable. 1. Which of the following drugs would you not recommend?
A. Cetirizine
B. Desloratadine
C. Diphenhydramine
D. Fexofenadine E. Loratadine
A 45-year-old man is to undergo chemotherapy for a testicular tumor.
2. Which of the following drugs is most likely to be used concomitantly as an antiemetic?
A. Bromocriptine
B. Ergotamine
C. Ibuprofen
D. Ondansetron
E. Sumatriptan
A 63-year-old man has glaucoma and requires treatment to lower the intraocular pressure.
3. Which of the following eicosanoids is most likely to be used?
A. Alprostadil
B. Dinoprostone
C. Latanoprost
D. Misoprostol
E. Prostacyclin
A 65-year-old woman comes to your office with a complaint of black stools and “feeling weak.” Stool testing for occult blood is strongly positive and her hemoglobin is 8 g/ dL (normal 12– 14 g/ dL). Medical history reveals that she has had rheumatoid arthritis for 15 years. On a doctor’s recommendation, she has treated her symptoms with aspirin with good control of her symptoms. Your diagnosis is gastrointestinal bleeding due to the NSAID.
4. Which of the following drugs will control her rheumatoid arthritis symptoms with the smallest risk of bleeding?
A. Diclofenac
B. Ibuprofen
C. Ketorolac
D. Naproxen
E. Valdecoxib
A 57-year-old man has been found in a screening program to have elevated total cholesterol (285 mg/ dL, desirable < 200 mg/ dL) and elevated triglycerides. He has a family history of early cardiovascular disease. 5. Which of the following drugs should not be used in his treatment?
A. Atorvastatin
B. Colestipol
C. Gemfibrozil
D. Lovastatin
E. Niacin
ANSWERS 1. The answer