1–16; May 2013; © 2013 Landes Bioscience Inhibition of the autophagic flux by salinomycin in breast cancer stem-like/progenitor cells interferes with their maintenance Wen Yue‚1‚2‚† Ahmed hamaï‚1‚2‚† Giovanni Tonelli‚1‚2 chantal Bauvy‚1‚2 Valérie Nicolas‚2‚3 hugo Tharinger‚2‚3 Patrice codogno1‚2 and Maryam Mehrpour1‚2‚* 1 † These authors contributed equally to this work. Keywords: breast cancer stem-like/progenitor cell‚ salinomycin‚ autophagy‚ cell death‚ lysosome Abbreviations: ACTB‚
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GENETIC INFLUENCE ON HUMAN BEHAVIOR Multiple situations and conditions can impair or influence human behavior in individuals. My hypothesis was genetics has the strongest influence on human behavior because of the inability to have control over heredity. Without control‚ how can one improve or change their behavior? Mental disorders can be inherited through genetics. Examples of genetically acquired mental disorders are schizophrenia and bipolar disorders. My personal experience with individuals
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MENDEL`S PRINCIPLES OF GENETICS 1.0 INTRODUCTION: 1.1 BACKGROUND Gregor Mendel‚ who is now considered as founder of classical genetics‚ ( Elrod S. & Stansfield w‚2010)‚ conducted a series of experiments using garden pea plants‚ his aim was to find a way of explaining to his fellow scientists who believed the blending theory which had been proposed earlier by Wiseman‚ that heredity involved the interaction of discrete separable factors (now known as genes) After a statistical analysis of the
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Aggression Discuss genetic factors involved in aggressive behaviour. The gene MAOA may be associated with aggressive behaviour. It is responsbile for breaking down neurotransmitters such as noradrenaline and dopamine after they have transmitted an impulse from one cell to another. The lower the MAOA gene‚means that the more aggressive the behaviour as dopamine and noradrealine is accumulated in their bodies. There has been emperical support by CASES et al who investigated mice genetically engineered
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Pancreatic Cancer "Cancer of the pancreas is a genetic disease that is the fifth most common cause of death in both men and women. Pancreatic cancer affects approximately 28‚000 Americans each year‚ or five out of 100‚000 people" (Mayo Clinic‚ 1998). According to physicians at Johns Hopkins Medical Institute‚ "pancreatic cancer is the challenge of the twenty-first century." So‚ where exactly is the pancreas located in our bodies‚ and what does it do? The pancreas is a gland found behind the stomach
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Q1.Some genetic disorders are caused by alleles inherited from the parents. (a) What are alleles? ........................................................................................................................ ........................................................................................................................ (1) (b) Describe how embryos can be screened for the alleles that cause genetic disorders. ..........................................................
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Treatment for Breast Cancer Magnetic resonance imaging guided focused ultrasound is completely noninvasive treatment for breast cancer which requires less anesthesia‚ recovery time and could avoid infections‚ scar formation and possibly reduce cost. It is the method of choice for accurate delimitation of many breast tumors‚ it can noninvasively measure ultrasound induced temperature. The combination of MRI and FUS concurrently allow the delineation of tumors margins (American cancer society).
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Azizjon Azimi Bioethics Long Stance Paper on Human Genetic Engineering The debate on whether human genetic engineering should be researched and used as the main alternative solution to disease have been going on since the creation of the "human genetic engineering" phenomenon. The ethical question is clear: should money be invested in human genetic engineering and should we research it at all‚ even if it is formally criticized by all monotheistic religions? The ethical principles in conflict
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Association for Molecular Pathology vs. Myriad Genetics The case of the Association for Molecular Pathology vs. Myriad Genetics was a case that challenged the validity of gene patents in the United States. It specifically challenged certain claims in issued patents owned or controlled by Myriad Genetics that cover isolated DNA sequences‚ methods to diagnose propensity to cancer by looking for mutated DNA sequences‚ and methods to identify drugs using isolated DNA sequences. Before this case occurred
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Genetic Engineering Cutting Edge Science By C.A.L.A. Consulting What Is Genetic Engineering? Genetic Engineering is the process of manually adding new DNA to an organism. The goal is to add one or more new traits that are not already found in that organism. When a gene for a desirable trait is taken from one organism and inserted into another‚ it gives the recipient organism the ability to express that trait. An accent‚ click to edit the text inside. An accent‚ click to edit the text inside
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