The nonmutated form of DMPK functions in the production of protein kinase serine; this enzyme plays a role in intracellular communication and in the regulation of myosin phosphate. When DMPK is mutated‚ the proteins CUG-BP1‚ MBNL1 and INSR are displaced causing the splicing of troponin pre-mRNA which causes malfunctions in the cardiac conduction system‚ dominance of a chloride channel that causes myotonia‚ dominance of an insulin receptor that affects the sufficiency of insulin‚ and dominance of
Premium Protein DNA Gene
Introduction: The pharmacokinetics of a drug describes the journey of a drug through the body i.e. its absorption‚ bioavailability‚ distribution‚ metabolism and excretion. Opioids are substances (endogenous or synthetic)‚ which produce ‘opiate-like effects’. Opiates are alkaloids derived from the Papaver somniferum poppy e.g. Morphine‚ Codeine (a morphine-like agonist) and Methadone (a synthetic analogue of morphine) and are primarily used as analgesics.[1] Discussion: Morphine has a 4-ring structure
Premium Opioid Morphine Drug addiction
Grignard Synthesis of Triphenylmethanol Aim The aim of this experiment was to prepared Grignard reagent (phenylmagnesium bromide) from bromobenzene and magnesium‚ to use the reagent prepared to synthesise a tertiary alcohol (triphenylmethanol) by reacting reagent and ester (methyl benzoate)‚ and the product formed is analyse by infrared spectroscopy (IR)‚ melting point‚ thin layer chromatography (TLC)‚ gas chromatography mass spectrum (GCMS) and finally Nuclear Magnetic Resonance spectroscopy. Introduction
Premium Nucleophile Magnesium Alcohol
purpose of a synthesis essay is to make insightful connections. Those connections can show the relationship(s) between parts of a work or even between two or more works. It is your job to explain why those relationships are important. In order to write a successful synthesis essay‚ you must gather research on your chosen topic‚ discover meaningful connections throughout your research‚ and develop a unique and interesting argument or perspective. A synthesis is not a summary. A synthesis is an opportunity
Premium Writing Essay Logic
Protein Synthesis Worksheet 1. 2. a. Protein synthesis began in the nucleus. b. Chromatin is a diffuse mass located in the nucleus where genetic material is found. c. A gene is a sequence of nucleotides‚ it is important because they form the template and these templates are used for synthesizing proteins. 3. a. Transcription is the first step of protein synthesis it uses a sequence of DNA nucleotides to produce a sequence of RNA nucleotide. b. RNA polymerase bonds to RNA nucleotides together
Premium Gene Protein DNA
SYNTHESIS OF SILVER NANOPARTICLES AND ITS CYTOTOXIC EFFECT AGAINST THP-1 CANCER CELL LINE 1 * Department of Biotechnology‚ Modern College‚ Shivajinagar‚ University of Pune‚ Pune‚ India. Mrs Rebecca Thombre email rebecca.thombre@gmail.com Telephone 9822224957 020 400966725 ABSTRACT: Nanotechnology is a field of science which involves the synthesis and applications of nanoparticles. Silver nanoparticles (AgNp) have applications in various fields due to their unique
Premium Leukemia Chemotherapy Cancer
Synthesis of Aspirin and Tylenol Kyla Wykoff Abstract Aspirin and Tylenol were synthesized by means of crystallization‚ recrystallization‚ and melting point determination. Synthesis produced significantly high percent yields for aspirin‚ however‚ produced extremely low and impure percent yields for Tylenol. A second group was also used to compare results and errors‚ in which they too were also producing extremely low percent yields of Tylenol. Therefore‚ error was based on the specific protocol
Free Aspirin
The structure and synthesis of TPC is outlined in Scheme 1. Briefly‚ the compound 1 was synthesized as per literature procedure. 2 was synthesized by reacting 1-methy pyrazole-4-boronic pinacol ester with 1 by suzuki-coupling‚ the final product TPC was synthesized by treating with malononitrile in the presence of piperidine as a base and ethanol as solvent. The detailed synthesis procedure given in the experimental section. The structure and purity of TPC was unambiguously confirmed by 1H and 13C
Premium Chemistry Acetic acid Alcohol
ACCOUNTING 505 SYNTHESIS |Key Features of a Synthesis | (1) It accurately reports information from the sources using different phrases and sentences; (2) It is organized in such a way that readers can immediately see where the information from the sources overlap;. (3) It makes sense of the sources and helps the reader understand them in greater depth. |The Background
Premium Source Research Writing
0.22g (percent yield of 86.9%). The percent yield after recrystallization‚ was 80.9%. INTRODUCTION The goal of this experiment was the synthesis of 3-nitrochalcone from 3-nitrobenzaldehyde and acetophenone as shown in Figure 1: Figure 1: Synthesis of 3-Nitrochalcone from 3-Nitrobenzaldehyde and Acetophenone Source: cnx.org The mechanism for the synthesis of 3-nitrochalcone is presented in Figure 2. The alpha carbon on the acetophenone is deprotonated‚ followed by the attack of the alpha carbon
Premium Oxygen Chemistry Alcohol