A General Review of Tetracyclines Antibiotics Chang Liu Instructor: Prof. Jasson Sello Department of Chemistry‚ Brown University Providence 02906‚ RI Tetracyclines are the first broad-spectrum antibiotic to be applied to clinic use. Nevertheless‚ the increasing incidence of bacterial resistance of tetracyclines led to a series of studies on the development of semisynthetic tetracyclines to circumvent the resistant organisms. In order to better design the structures of tetracycline derivatives
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What is it? Docetaxel is a FDA approved chemotherapy drug. It can treat breast‚ lung‚ prostate‚ stomach‚ and head and neck cancer. Its trade name is Taxotere. It needs to be prescribed by a doctor.. Docetaxel is used in treating cancer; it attacks the cancer cells. It does so by stopping the cancer cell from growing into two new cells. It basically stops the growth of cancer. It belongs to a class of chemotherapy drugs referred to as plant alkaloids. The alkaloid is one of the taxane type drugs
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Global J. of Mod. Biol. & Tech.‚ 2012: 2 (3) Research Paper: Arunkumar et al.‚ 2012: Pp.68-72. ISOLATION AND CHARACTERIZATION PHYTASE PRODUCING MICROBES FROM POULTRY SOIL SAMPLE Arunkumar.R.‚ Bharath Chandra Sugunesh. G and A.M. Vinothkumar Dept. of Biotechnology‚ Prathyusha Institute of Technology and Management‚ Thiruvallur-25. ABSTRACT Phytase producing thirteen microbial strains were identified in poultry soil sample collected at Sathyamangalam‚ Erode district‚ Tamilnadu. Among thirteen isolates
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2010-09-16 Experiment 19: Fischer Esterification‚ Conclusion The objective in this experiment was to efficiently perform an Fischer esterification of 1-butanol and acetic acid to form water and n-butyl acetate‚ and to confirm the esterification using IR spectroscopy analysis. It was found that 0.734 grams of n-butyl acetate was formed with a percent yield of 61%. The product was confirmed using IR spectroscopy and boiling point confirmation. The reaction mechanism for this specific reaction was as follows:
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Experiment 5B: Ketone Reduction Objective: Using sodium borohydride as a reducing agent‚ the ketone 4-tert-butylcyclohexane is reduced to its corresponding alcohol. It is purified through extraction techniques to give the cis and trans diasteromer products. Procedure: The procedure was followed as outlined in Mayo’s book for Experiment 5B with the following modifications: 1. Reagents and Equipment – The reaction will be on a scale of 2X what is described in the text. 2. Reagents and Equipment
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users of its products‚ such as butyl and halobutyl‚ are manufacturers of automobile tires; other users are from various industries. In 1986‚ Rubber group contributed 0.8 billion which is 46 percent of the company annual sale. The operation of the group is divided into four divisions‚ NASA (North America and South America) and EROW (Europe and rest of the world)‚ Research department and Global Marketing department. NASA and EROW operate as profit centers each produce butyl and halobutyl dedicated to regional
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users of its products‚ such as butyl and halobutyl‚ are manufacturers of automobile tires; other users are from various industries. In 1986‚ Rubber group contributed 0.8 billion which is 46 percent of the company annual sale. The operation of the group is divided into four divisions‚ NASA (North America and South America) and EROW (Europe and rest of the world)‚ Research department and Global Marketing department. NASA and EROW operate as profit centers each produce butyl and halobutyl dedicated to regional
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Elimination Reactions ________________________________________ As described previously‚ primary alkyl halides generally undergo substitution reactions with simple nucleophiles by an SN2 mechanism. Secondary alkyl halides‚ often react with simple basic nucleophiles to give a mixture of products arising from both substitution and elimination. As with substitution reactions‚ the rate at which elimination reactions proceed can be proportional to both the concentration of the base and the concentration
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produced 46% of Polysar sales Group 3 - 2/13 • NASA - Sarnia 1 Plant : Produce Butyl & HaloButyl → HaloButyl (from 1984) - Sarnia 2 Plant : Produce Butyl (operation 1984) 1) 1984 : 95‚000 t 2) 1985 : 65‚000 t • EROW - Antwel plant : Produce Butyl & HaloButyl (1964‚ 1979 modified) 1) 1981 : Prduced Butyl(75%) & HaloButyl(25%) 2) 1985 : Prduced Butyl(50%‚ 45‚000t)‚ HaloButyl(50%‚ 45‚000t) Transfer NASA to ERROW : Butyl(21‚000t) Group 3 - 3/13 Q1. The meaning and accuracy of the volume variance
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INTRODUCTION The main theory behind this experiment is that by setting up several apparatuses using varying amount of t-butyl alcohol‚ distilled water‚ or an unknown liquid‚ the freezing point of t-butyl alcohol‚ the molal freezing point and the molar mass of an unknown can be determined. The equations pertinent to this experiment include the following: mc= ∆Tf=Tf-Tf’=(Kf)(mc) mc= mc= mc= gram molar mass of solute‚ g mole^-1= kf=∆Tf/ mc mass of unknown ‚g=(volume of
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