Amyotrophic Lateral Sclerosis ( Greek origin "A" means know, "Myo" refers to muscle, "Trophic" means nourishment ["No muscle nourishment"] with abbreviation of ALS) is a disease that effects the nervous and muscular system of the body. It was first studied in 1869 by Jean- Martin Charcot who was a French neurologist. In 1939 it gained international and national attention thanks to a man named Lou Gehrig. Gehrig was a baseball player for the New Year Yankees who ended up having to retire for the sport he loved because of his diagnosis of ALS, therefore Amyotrophic Lateral Sclerosis got its more common name Lou Gehrig's Disease. (ALS Association, 2016) Causes for ALS is still under investigation. Five …show more content…
There is research that has been conducted that has however, lead some scientist to believe that it could be linked to genetics, chemical imbalances, disorganized immune response, or even mishandling of proteins. ALS affects homeostasis by causing motor neurons that are found in the spinal cord and brain to start to degenerate and die off. This causes signals to the muscles to "turn off" and the muscles become un-operable causing weakening which results in the muscle wasting away. It will eventually lead to the in-operation of the involuntary muscles such as the heart which in the end leads to …show more content…
Symptoms of ALS often times start out in the feet, arms, legs, and hands. Patients may experience weakness in lower limbs, hands may become weak and clumsy, may have trouble walking and doing everyday activities, and tripping/falling more often than normal. As this disease progresses it will start to affect your facial muscles (muscles used for chewing, swollowing, talking, and even breathing). The patients minds and cognitive skills will not be affected and it normally does not affect the bladder or bowels.
The nervous system and most of the muscle system is affected by ALS. Once diagnosed with ALS most patients live two to five years but death is always the end result because of the effect on vital muscles. Patients who may be experiencing these may need to have other test run to make sure that their symptoms are not some other disease or disorder that may start out very similar to ALS. These other diseases/disorders include Primary Lateral Sclerosis (PLS), Progressive Bulbar Palsy (PBP), or Spinal Muscular Atrophy (Werdnig-Hoffmann disease)
Diagnostic Test for Amyotrophic Lateral