audience analysis memo
Memorandum
To:
CC:
From:
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Re:
In accordance with the Week 1 assignment, I have chosen the following two internet sites to analyze and contrast: http://www.ncbi.nlm.nih.gov/pubmed/16334941, and http://www.maxavita.com/equinejointsupplement.htm. The subjects of these sites are the compound Chondroitin Sulfate and an amino sugar, Glucosamine, which are typically compounded together in an oral formulation and marketed as an equine joint supplement. They are widely used by horse owners and trainers in an attempt to alleviate pain and unsoundness caused by osteoarthritis.
The site from PubMed (http://www.ncbi.nlm.nih.gov/pubmed/16334941) is designed for veterinarians and veterinary researchers. In addition, researchers for human medicine may likely be a secondary audience, as many trials are utilized on animals without quite as many constraints and restrictions as those when utilizing human beings. The article was published in the American Journal of Veterinary Research and is peer-reviewed. This article does support Glucosamine as being beneficial in treating osteoarthritis, but states that chondroitin sulfate had no effect at the concentration amount used in the test. The data is clearly presented to support these conclusions. The material appears to be presented in an unbiased format. The intent is to present the results of a trial, not as intent to promote a product. The language is technical and the jargon reflects that of an audience which is well educated in chemistry and biology. The sentences are frequently long and often complex, such as Effects of prior incubation with glucosamine (2.5 to 10.0 microg/mL) and CS (5.0 to 50.0 microg/mL) on gene expression of matrix metalloproteinase (MMP)-1, -2, -3, -9, and -13; aggrecanase 1 and 2; inducible nitric oxide synthase (iNOS); cyclooxygenase (COX)-2; nuclear factor kappaB; and c-Jun-N-terminal kinase (JNK) were assessed by use of a quantitative real-time polymerase chain reaction assay. (PubMed,
To:
CC:
From:
Date:
Re:
In accordance with the Week 1 assignment, I have chosen the following two internet sites to analyze and contrast: http://www.ncbi.nlm.nih.gov/pubmed/16334941, and http://www.maxavita.com/equinejointsupplement.htm. The subjects of these sites are the compound Chondroitin Sulfate and an amino sugar, Glucosamine, which are typically compounded together in an oral formulation and marketed as an equine joint supplement. They are widely used by horse owners and trainers in an attempt to alleviate pain and unsoundness caused by osteoarthritis.
The site from PubMed (http://www.ncbi.nlm.nih.gov/pubmed/16334941) is designed for veterinarians and veterinary researchers. In addition, researchers for human medicine may likely be a secondary audience, as many trials are utilized on animals without quite as many constraints and restrictions as those when utilizing human beings. The article was published in the American Journal of Veterinary Research and is peer-reviewed. This article does support Glucosamine as being beneficial in treating osteoarthritis, but states that chondroitin sulfate had no effect at the concentration amount used in the test. The data is clearly presented to support these conclusions. The material appears to be presented in an unbiased format. The intent is to present the results of a trial, not as intent to promote a product. The language is technical and the jargon reflects that of an audience which is well educated in chemistry and biology. The sentences are frequently long and often complex, such as Effects of prior incubation with glucosamine (2.5 to 10.0 microg/mL) and CS (5.0 to 50.0 microg/mL) on gene expression of matrix metalloproteinase (MMP)-1, -2, -3, -9, and -13; aggrecanase 1 and 2; inducible nitric oxide synthase (iNOS); cyclooxygenase (COX)-2; nuclear factor kappaB; and c-Jun-N-terminal kinase (JNK) were assessed by use of a quantitative real-time polymerase chain reaction assay. (PubMed,
References: Effects of glucosamine and chondroitin sulfate ... [Am J Vet Res. 2005] - PubMed - NCBI. (n.d.). Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/16334941 MaxaFlex | Equine Joint Supplement. (n.d.). Retrieved from http://www.maxavita.com/store/products,maxaflex_23.htm