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Autism
This paper appeared in Autism, 1998, 2, 296-301.

Autism occurs more often in families of physicists, engineers, and mathematicians.

Simon Baron-Cohen , Patrick Bolton, Sally Wheelwright, Victoria Scahill Liz Short, Genevieve Mead, and Alex Smith

Departments of Experimental Psychology and Psychiatry, University of Cambridge, Downing St, Cambridge, CB2 3EB, UK.

To whom correspondence should be addressed.

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Abstract

The study reported here tests a prediction that autism should occur more often in families of individuals whose occupation requires advanced folk physics but with no requirement of good folk psychology. Physics, engineering, and mathematics are paradigm examples of such occupations. Students in Cambridge University, studying one of these 3 subjects, were screened for cases of autism in their families. Relative to a control group of students studying literature, autism occurred significantly more often in families of students in the fields of physics, engineering, and mathematics.

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Autism is considered to be the most severe of the childhood psychiatric disorders. It is strongly heritable (Bailey et al., 1995) and is diagnosed on the basis of abnormalities in social development, communication, and imagination (APA, 1994). First-degree relatives of children with autism are at raised risk not only of autism itself, but also of a lesser variant (or broader phenotype) of autism (Baron-Cohen & Hammer, 1997; Bolton et al., 1994). One model proposes that the broader phenotype might be characterised as involving deficits in ‘folk psychology’ (social understanding) in the presence of intact or superior abilities in ‘folk physics’ (understanding inanimate objects) (Baron-Cohen, in press).

This study builds on the notion that cognition has a domain-specific structure (Barkow, Cosmides & Tooby, 1992; Gelman & Hirschfield, 1994), i.e., that cognitive domains exist in the human brain, as a result of natural selection. Two such basic



References: Andreasen, N. (1987). Creativity and mental illness: Prevalence rates in writers and their first-degree relatives. American Journal of Psychiatry, 144, 1288-1292. APA. (1994). DSM-IV Diagnostic and Statistical Manual of Mental Disorders, 4th Edition. Washington DC: American Psychiatric Association. Bailey, T., Le Couteur, A., Gottesman, I., Bolton, P., Simonoff, E., Yuzda, E., & Rutter, M. (1995). Autism as a strongly genetic disorder: evidence from a British twin study. Psychological Medicine, 25, 63-77. Baillargeon, R., Kotovsky, L., & Needham, A. (1995). The acquisition of physical knowledge in infancy. In D. Sperber, D. Premack, & A. Premack (Eds.), Causal Cognition: A Multidisciplinary Debate, . Oxford: Oxford University Press. Barkow, J., Cosmides, L., & Tooby, J. (1992). The Adapted Mind. New York: Oxford University Press. Baron-Cohen, S. (1995). Mindblindness: an essay on autism and theory of mind.: MIT Press/Bradford Books. Baron-Cohen, S. (in press). Are children with autism superior at folk physics? In H. Wellman & K. Inagaki (Eds.), Children 's theories. New Direction for Child Development Series, : Jossey-Bass Inc. Baron-Cohen, S., & Hammer, J. (1997). Parents of children with Asperger Syndrome: what is the cognitive phenotype? Journal of Cognitive Neuroscience, 9, 548554. 8 Baron-Cohen, S., Jolliffe, T., Mortimore, C., & Robertson, M. (1997). Another advanced test of theory of mind: evidence from very high functioning adults with autism or Asperger Syndrome. Journal of Child Psychology and Psychiatry, 38, 813-822. Baron-Cohen, S., Leslie, A. M., & Frith, U. (1985). Does the autistic child have a 'theory of mind '? Cognition, 21, 37-46. Baron-Cohen, S., Leslie, A. M., & Frith, U. (1986). Mechanical, behavioural and Intentional understanding of picture stories in autistic children. British Journal of Developmental Psychology, 4, 113-125. Baron-Cohen, S., Wheelwright, S., Stott, C., Bolton, P., & Goodyer, I. (1997). Is there a link between engineering and autism? Autism: An International Journal of Research and Practice, 1, 153-163. Bolton, P., MacDonald, H., Pickles, A., Rios, P., Goode, S., Crowson, M., Bailey, A., & Rutter, M. (1994). A Case-Control Family History Study of Autism. Journal of Child Psychology and Psychiatry, 35, 877-900. Claridge, G., Pryor, R., & Watkins, G. (1990). Sounds from the Bell Jar: Psychotic Authors. London: Macmillan. Gelman, S., & Hirschfield, L. (1994). Mapping the Mind. Cambridge: Press Syndicate, University of Cambridge. Gergely, G., Nadasdy, Z., Gergely, C., & Biro, S. (1995). Taking the intentional stance at 12 months of age. Cognition, 56, 165-193. Leekam, S., & Perner, J. (1991). Does the autistic child have a metarepresentational deficit? Cognition, 40, 203-218. 9 Leslie, A., & Keeble, S. (1987). Do six-month old infants perceive causality? Cognition, 25, 265-288. Leslie, A. M., & Thaiss, L. (1992). Domain specificity in conceptual development: evidence from autism. Cognition, 43, 225-251. 10

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