Typically, one of the areas which is less actively wired than average, for high functioning autism people is the area dealing with innate comprehension of some social interactions, and some other functions which are processed in the same area. This means that some things just "don 't come naturally" in the way that they do with neuro typical people. Also, high functioning autistic people will have one or more things which come naturally to them which don 't for neuro typical people. There is often a difference in the way that language is processed, too, which makes learner and understanding harder as well.
People with autism struggle with many issues. Anxiety, ADHD, and depression all play a factor in the daily lives of those who have some form of autism. The key to helping them work anything and to help avoid the actions caused by ADHD and depression is to help the person avoid issues that cause the anxiety. In order to do this, you must first find the trigger points that cause the anxiety. For someone who is neuro typical, anxiety results from issues that become very stressful to us. Things like losing a partner, our job, unable to pay our bills will heighten our anxiety levels. For a person with autism, not being able to find their favorite pair of sock is all it takes for them to feel the intensity of high levels of anxiety.
People with autism have trouble with being able to keep most things organized. It doesn’t matter how intelligent
References: Moreno, S. J & O’Neal, C (2000). Tips for teaching high functioning people with autism. Crown Point, In