The intertwined factors cited include a parasitic mite, multiple viruses, bacteria, poor nutrition, genetics, habitat loss and pesticides.
The multiple causes make it harder to do something about what's called colony collapse disorder, experts say. The disorder has caused as much as one-third of the nation's bees to just disappear each winter since 2006.
Bees, especially honeybees, are needed to pollinate crops.
The federal report, issued Thursday by the Agriculture Department and the Environmental Protection Agency, said the biggest culprit is the parasitic mite varroa destructor, calling it "the single most detrimental pest of honeybees."
The problem has also hit bee colonies in Europe, where regulators are considering a ban on a type of pesticides known as neonicotinoids that some environmental groups blame for the bee collapse. The U.S. report cites pesticides, but near the bottom of the list of factors. And federal officials and researchers advising them said the science doesn't justify a ban of the pesticides yet.
May Berenbaum, a top bee researcher from the University of Illinois, said in an interview that she was "extremely dubious" that banning the pesticide would have any effect on bee health. She participated in a large conference of scientists that the government brought together last year to figure out what's going on, and the new report is the result of that conference.
Berenbaum said more than 100 different chemicals — not just the pesticides that may be banned in Europe — have been found in bee colonies. Scientists find it hard to calculate how they react in different dosages and at different combinations, she said.
Some of these chemicals harm the immune systems of bees or amplify viruses, said Penn State University bee expert Diana Cox-Foster.
At a news conference Thursday, Sonny Ramaswamy, a top USDA official,