Brown Mouse Observation

In stage one, the hole count was left at fourteen. The mice were not on any psychoactive substances at this time. The white mouse was able to find her way to the end of the maze at 1 minute. She showed signs of stress, and overall anxiousness. The brown mouse was slower then her counterpart, completing the maze at 2 minutes and 53 seconds. She also showed signs of stress and discomfort. Lastly, the black mouse found the cheese in 10 seconds, but discovered and explored the whole maze in 2 minutes and 30 seconds. Overall, these weren’t bad scores for mice that were in their normal state of mind. Besides the stress and anxiety of me trying to catch them, picking them up, and putting them in a mysterious box with the exits closed off, the mice
preformed rather well. Things got interesting as I feed each one of them the different substances. For the white mouse, I gave her the psychoactive noopept. A dosage of nearly 15 mg added to cheese, the mouse quickly grabbed the cheese, and ate it. The ingestion time was 8:40, and I waited for around tweet minutes, giving the drug time to kick in without fully wearing off either. The white mouse showed sings of energy, curiosity, and loss of fear. The mouse was able to start at the beginning of the maze, and complete it in 30 seconds, cutting her original time in half. This was a strong improvement, and showed promising signs. Once I released the mouse back into her cage, she ran on the wheel I have installed for a good 1-2 minutes, showing me that they had a uptake in energy. This certainly lives up to the fact sheet of positive effects that noopept has on mammals, that of increase in energy, focus, and learning. But how does it compare to the other nootropics used in this experiment? To answer this, the next mouse to be used in the experiment was the brown mouse.
The brown mouse was given 50 mg of aniracetam. The consumption time was at 10:10 PM, with a wait time of 40 minutes since the peak for the effects of this smart drug is between 30 minutes to 60 minutes. The brown mouse was calm at first, and I thought she would be ready for the experiment. However, the drug seemed to not work too well to calm him down enough to fully explore the maze. The completion time was above one minute before I stopped the watch since she would not continue the experiment. She showed signs of distress, heavy breathing, and was very agitated and anxious once I released her back into her cage. The black mouse, who commonly associates with the brown one and plays with them, the brown mouse made a variety of squeals and noises, and scratched/pawed the other mouse of some sort. I decided to let the mouse be, and to not conduct any more experiments for her because of her
distress. Things took a positive turn however, when the black mouse was given a dosage of 10 mg of sunifiram that was added to cheese, as well as sprinkled onto some of the mouse food I had. At first, the black mouse ignored the food, and instead wanted to get to the other mouse in the closed off section of the maze, who at that time, was eating the aniracetam laced cheese and food. The black mouse did end up eating the laced cheese and food after a few minutes past, around the time of 9:30. I waited about 20 to 30 minutes for the effects of the drug to kick in, since sunifiram doesn’t take a decent amount of time to kick in, and only has a half life of sixteen to thirty minutes. At first, the black mouse finished the maze within the one minute range, cutting their original time of a little over 2 minutes in half. Once I released the mouse back into its cage, and reinstalled the running wheel that I took down so they wouldn’t hide under, the mouse went straight to it, burning off his increased energy. After observing this, I decided it would be best to put the mouse back into the maze to test how well it would preform, since it seemed to have an increase in energy and curiosity compared to when I last tested her. The black mouse showed a huge sign of improvement by completing the maze in 35 seconds, really beating down its initial time of 2 minutes. The mouse no longer showed anxiety, and instead showed the ability to control its anxiety and fear, handling the test course in a fairly low time. This was outstanding, and really impressed me. Laslty, after the mice ingested the sunifiram, aniracetam, and noopept, I wanted to see how they would like the adderall.
This however, turned out to be the most challenging task. The mice learned what the cheese was being used for in my observation, as they would sniff it, and then all of them would refuse to eat it. I decided to put the adderall into their water supply, and to nudge the white mouse towards it. The white mouse showed no interest in it. Instead, he only sniffed it, and then retreated to burrow under the mesh that was in the cage. The brown mouse would not drink the laced water either, and went to cuddle with the white
mouse. The black mouse was some what of a tease, as they would sniff the water, climb up on the side of the food container that I emptied out to put water in, and leaned down to get a drink. They however, would only sniff it, circle around on the container, lean down, sniff it again, and leave. They did this for a total of ten minutes. I believed that they would end up drinking the water, but it seemed that they could tell it was not their normal water. The adderall section of this experiment was a failure, but once that proved insightful none the less. The mice’s reactions to the laced food and water altering taking nootropics seemed to only suggest that some of the effects of nootropics listed by fourms, medical websites, and psychonuats was indeed true. The mice showed signs of learning that something about their food was not entirely right, and thus, they would not bother to drink or eat from it. I decided to place the cheese with the mouse food, as they ate some of the food, signaling to me that their undesired interest in the water and cheese was not due to loss of appetite commonly associated with stimulates and some nootropics. The mice, crowding around the food, ate it, but completely skimmed over the cheese, and even steeped on it, mushing it down into the mesh. I decided to try and sprinkle some of the adderall onto the mouse food, but they simply sniffed it, and moved on. This was frustrating for me, but as stated before, it signaled to me that the mice had learned, rather quickly that their food was being laced. They would only eat the normal untampered food, and showed no interest in the cheese. If I had to do this experiment again, I do not know how I would get the mice to eat the tampered with food. Their ability to learn quickly and their memory increase most likely made them realize that their food was laced. I believe that if I added some sort of sugar, and/or flavoring to the water then they might have not thought twice about ingesting it. The nootropics and adderall have a distinctive, and sometimes bitter taste. The adderall is not bitter so to speak as noopept might be, but it would still lead the water to taste off, or smell off. The conditions of the environment might have thrown them off, as might cat was initially in the room, and wouldn’t budge. However, I removed Bandit, my cat, from the room, and closed the door. I had a nice room temperature set, a fan blowing, and the windows open to allow air circulation. The maze was new, clean, and was well constructed. The mice had cheese, mouse food, and water for their hunger and thirst. A wheel is set up in the cage to allow them to play and burn off their energy. The conditions of my environment most likely did not have any negative effects on the mice, as I have had them in this environment for the last four days. I do believe however that picking them up over a six hour period, taking them away from their friends, and putting them into an unknown, mysterious place most likely caused shock. This was obvious as the mice would experience rapid breathing, getting agitated and showing aggressiveness towards the other mice for a short period of time, and releasing a large amount of feces on the mesh as well as the maze. The brown mouse did this more so then the other mice, as she seemed to experience more anxiety then the rest. This was rather unsuspected from me, as aniracetam is known to give the user suppression of anxiety. Once placed into the maze, she showed anxiety. When he ate however, his rapid breathing did stop, and she showed curiosity about the black mouse on the other side of her. I removed the black mouse from the maze when they were done eating, and took down the blocked hole so they wouldn’t associate with each other at the time being. Something about this made the brown mouse very anxious and agitated, resulting in a bad timing recorded when I made the brown mouse start from the beginning again. The results recorded with this mouse could have been flawed, as the mouse was in a panicking state of mind. Sunifiram showed better anti-anxiety results for the black mouse at least, as it did not show anxiety when completing the course. This is not too surprising for me, as sunifiram is a rather powerful, potent nootropic research chemical that has near the same potency over piracetam that noopept has, over one thousand to five thousand times that of the earlier. This showed promising signs, and I would be sure to test sunifiram in higher doses, as well as in combinations with other nootropics, also known as ‘stacking’. It would be interesting to see how other mice, such as male mice, and not just female mice, would handle potent nootropics such as this one. From my observations, I would recommend sunifiram to persons who are willing to try it, and do their research on the drug before consumption. I am not advocating its use for everyone, but it no doubt shows promising signs. Lastly, we have noopept. Noopept preformed with an identical time as sunifiram did, with the white mouse cutting his original time in half, beating sunifiram by only five seconds. This does not prove that sunifiram is not as strong as noopept, as it could have been the white mouse’s performance and state of mind for adventure and curiosity was higher at this given point in time then the black mouse. This close time proximity of noopept and sunifiram does however, lead me to believe that both the nootropics are very strong, and live up to their expectations of high potency compared to other nootropics. The mice, given both sunifiram, and noopept both showed a higher sense of faster learning, memory increase for recognizing parts of the maze, as well as an increase in adventure and decrease in anxiety compared to the brown mouse that ingested aniracetam. This experiment certainly is not to be trusted as one conducted in a professional laboratory with more test subjects, better conditions, and more observation techniques, but it does go to show that indeed there is a difference between the mice that went through the initial maze without nootropic drugs in their system, versus when they went through a changed, more mysterious maze with smart drugs flowing through their system. The applications of using smart drugs are endless, as stated before, and from my observations of these mice, it certainly does show improvement in cognitive ability and control of stress and fear. This can be helpful for people suffering from anxiety disorders, depression disorders(as in the case of sunifiram), and for those looking for an extra edge above their peers in the workforce or in school. More research needs to be conducted and professional persons are needed to conclude their statements and thoughts on their use.