Case Study: The Term Compliance
INTRODUCTION
“Compliance” implies the degree to which a patient takes a medication as it has been prescribed. [1] The term compliance has largely been replaced by “adherence” for practical purposes; however the latter denotes negative connotations. [2] The term “medication adherence” is defined by NICE as the extent to which the patient’s action matches the agreed recommendations of the prescriber. [3] “Adherence” seems to imply a patient’s choice to follow prescribed therapy, while “compliance” implies certain passivity to another’s request. Throughout this study, both terms will correspond to describe agreement between prescription and practice, since the extent to which any patient adheres or complies with a prescribed medication regimen …show more content…
Loss to follow-up was a major concern (45.1%, Q4). (Table 3) ICS prescriptions were most frequent in boys of young category (8-10 years). Children in this sample represented a wide range of compliance, from those who took none of their prescribed doses during the study period (2.3%) to those who took practically all of their prescribed doses (28.4%). Mean level of good compliance (MPR > 80%) across children of all age group was 0.40 ± 0.18 (median = 0.41). Median MPRs for ICS and ICS/LTRA was 37.5% and 33.5% respectively (p = ns). Good compliance (MPR > 0.8) was observed only in 41.2% of ICS users and 40.5% ICS/LTRA users (p = ns). However, overall mean compliance was 0.35 ± 0.12 (median = 0.39), indicating that, on average, children took less than half of their prescribed preventive medications.
Compliance did not differ with respect to age (r = 0.16, p = 0.072); gender (r = -0.06, p = 0.495); religion (r = 0.027, p = 0.770); SES (r = -0.063, p = 0.495); education of caregiver (r = 0.125, p = 0.177) or area of residence (r = 0.110, p = 0.234) in our study cohort. Covariates like asthma duration (r = 0.138, p = 0.135); family history of asthma (r = 0.059, p = 0.409); co-morbid conditions (r = -0.076, p = 0.409) and age at start of asthma therapy (r = 0.065, p = 0.478) seemed unrelated to the degree of
“Compliance” implies the degree to which a patient takes a medication as it has been prescribed. [1] The term compliance has largely been replaced by “adherence” for practical purposes; however the latter denotes negative connotations. [2] The term “medication adherence” is defined by NICE as the extent to which the patient’s action matches the agreed recommendations of the prescriber. [3] “Adherence” seems to imply a patient’s choice to follow prescribed therapy, while “compliance” implies certain passivity to another’s request. Throughout this study, both terms will correspond to describe agreement between prescription and practice, since the extent to which any patient adheres or complies with a prescribed medication regimen …show more content…
Loss to follow-up was a major concern (45.1%, Q4). (Table 3) ICS prescriptions were most frequent in boys of young category (8-10 years). Children in this sample represented a wide range of compliance, from those who took none of their prescribed doses during the study period (2.3%) to those who took practically all of their prescribed doses (28.4%). Mean level of good compliance (MPR > 80%) across children of all age group was 0.40 ± 0.18 (median = 0.41). Median MPRs for ICS and ICS/LTRA was 37.5% and 33.5% respectively (p = ns). Good compliance (MPR > 0.8) was observed only in 41.2% of ICS users and 40.5% ICS/LTRA users (p = ns). However, overall mean compliance was 0.35 ± 0.12 (median = 0.39), indicating that, on average, children took less than half of their prescribed preventive medications.
Compliance did not differ with respect to age (r = 0.16, p = 0.072); gender (r = -0.06, p = 0.495); religion (r = 0.027, p = 0.770); SES (r = -0.063, p = 0.495); education of caregiver (r = 0.125, p = 0.177) or area of residence (r = 0.110, p = 0.234) in our study cohort. Covariates like asthma duration (r = 0.138, p = 0.135); family history of asthma (r = 0.059, p = 0.409); co-morbid conditions (r = -0.076, p = 0.409) and age at start of asthma therapy (r = 0.065, p = 0.478) seemed unrelated to the degree of