First evidence is …show more content…
“Staining with specific dyes showed major …show more content…
Because the cyanide prevents the transfer of electron to oxygen, the mitochondria will be damaged, then oxygen will flew back to the blood. In electron transport chain of cellular respiration, oxygen is the accepter of electrons, it moves to the end of protein IV and bonds with hydrogen by electrons to form H2O. However, if the number of oxygen decreased, the electrons would be stuck in the protein IV, then the protein III , protein II and protein I, and the whole chain will be blocked, which means the hydrogen ion cannot pass the membrane from the inner to outside and the concentration of hydrogen ion of both side will be balanced. Therefore the diffusion will stopped and no more ATP will be produced by chemiosmosis. Also, the number of NADH will increased, in contrast, the NAD+ will reduced, and the rate of the process of Glycolysis and The Citric Acid Cycle will slow down, The whole metabolism system will be delayed or stopped. Without the energy the organ of human body will be exhausted and prostrated. The evidence of the data of levels of key metabolites can support this inference. The level of glucose and pyruvate are normal, but the level of NAD+ is extremely low and in opposite the level of NADH (electron carrier)us extremely high.
Hence, the directly cause of seven deaths is cyanide, and the indirect cause of that is metabolic damaged. This study indicates that the importance of cellular respiration, it’s the