Seed kernel of Cucumis melo L. has shown therapeutic effect against infections associates with genitourinary tract. This is shown in a review on medicinal herbs in the treatment of renal disorders in Pakistan (Ullah et al., 2015). It showed that seed kernel of Cucumis melo linn. was used in traditional medicine to treat painful micturition, urinary tract ulcers, dysuria, kidney and bladder stones, chronic fever and other inflammations in kidney and liver. It was further stated that due …show more content…
Chronic unpredictable mild stress (CUMS) protocol was used to induce stress in rats and the anti-depressant activities were determined by forced swimming test (FST). Results revealed that hydroethanolic extract of Cucumis melo shows anti-stress activity. Mild anxiolytic activity was also shown which might be due to part of its antioxidant activity (Doss, Sowandarya and Sandiya, 2015).
Leaf extracts of Cucumis melo is well known to possess anti-hyperglycemic activity. Babulreddy et al., (2013) conducted a study to investigate anti-hyperglycemic activity of Cucumis melo leaf extracts in streptozotocin (55 mg/ kg) induced hyperglycemia in rats. Study results revealed that, doses of 300 mg/ kg and 500 mg/ kg reduced the serum glucose levels when compared to the control and standard group rats in both the extracts with a greater anti-hyperglycemic activity in methanolic extract compared to the aqueous …show more content…
against bacterial species and fungal species have shown that the antibacterial effect was higher against fungal species. In a study by Karim, Asma and Kamal et al., (2016) in vitro antimicrobial activity of Sudanese Cucumis melo L. fixed oil was investigated. Agar cup diffusion assay was performed against two fungal species (Candida albicans and Aspergillus niger), two gram positive bacteria (Staphylococcus aureus and Bacillus subtilis) and two gram negative bacteria (Escherichia coli and Pseudomonas aeruginosa). Ampicillin, gentamycin and clotrimazole were used as positive controls. Antimicrobial activity was shown by all the species except E.coli and P. aeruginosa. Oil showed a highest activity against Candida albicans with an inhibition zone of 19mm and a partial activity of 12mm against Staphylococcus aureus. A similar study was done in Bangladesh on the isolation, physico-chemical characterization and microbial activities of melon (Cucumis melo) seed oil (Ahamed et al., 2014). The antimicrobial activity was studied on four bacterial species (Staphylococcus aureus, Escherichia coli, Salmonella typhi and Bacillus cereus) and four fungal species (Aspergillus funiculosus, Fusarium equiseti, Curvularia lunata and Alternaria alternate). Oil samples of 1% and 10% showed activity against all test microbes except for Curvularia lunata. From bacterial species, highest inhibition zone (19 mm) was observed