Data Handling
nutrient Metabolism
Dietary Chromium Supplementation with or without
Somatotropin Treatment Alters Serum Hormones and Metabolites in Growing Pigs without Affecting
Growth Performance1«2
CHRISTINA M. EVOCK-CLOVER,3 MARILYN M. POLANSKY,*
RICHARD A. ANDERSON*
AND NORMAN C. STEELE
Nonruminant Animal Nutrition Laboratory and *Vitamin and Mineral Nutrition Laboratory,
USDA-Agricultural Research Service, Beltsuille, MD 20705
increase in insulin internalization in rat muscle cells
(Evans and Bowman 1992) with a concomitant in crease in glucose and leucine uptake. Chromium chloride and chromium nicotinate had no effect.
Chromium supplementation to diets of pigs has been shown to increase the percentage of muscle by
7% and longissimus dorsi muscle area by 18%, while reducing 10th rib fat 20% and serum cholesterol 19%
(Page et al. 1993) when fed from 30 kg body weight until slaughter at 100 kg. Chromium response was specific for CrP. Other forms tested, including chromium chloride, were without effect. Similarly, porcine somatotropin
(pST) markedly improves growth performance and carcass composition of pigs
'Mention
INDEXING KEY WORDS:
of a trade name, proprietary
product or vendor does
not constitute a guarantee or warranty of the product by USDA or imply its approval to the exclusion of other products or vendors that also may be suitable.
2The costs of publication of this article were defrayed in pan by
•pigs •chromium •somatotropin •growth
the payment of page charges. This article must therefore be hereby marked "advertisement" in accordance with 18 USC section 1734 solely to indicate this fact.
3To whom correspondence should be addressed: USDA-ARS,
NANL, Bldg. 200, Room 201, BARC-East, 10300 Baltimore Blvd.,
Beltsville, MD 20705.
4Abbreviations used: CrP, chromium picolinate; IGFBP, insulinlike growth factor binding protein,- IGF-1, insulin-like growth factor
1; ppST, pituitary porcine somatotropin; pST, porcine somatotropin.
Chromium is an essential
Dietary Chromium Supplementation with or without
Somatotropin Treatment Alters Serum Hormones and Metabolites in Growing Pigs without Affecting
Growth Performance1«2
CHRISTINA M. EVOCK-CLOVER,3 MARILYN M. POLANSKY,*
RICHARD A. ANDERSON*
AND NORMAN C. STEELE
Nonruminant Animal Nutrition Laboratory and *Vitamin and Mineral Nutrition Laboratory,
USDA-Agricultural Research Service, Beltsuille, MD 20705
increase in insulin internalization in rat muscle cells
(Evans and Bowman 1992) with a concomitant in crease in glucose and leucine uptake. Chromium chloride and chromium nicotinate had no effect.
Chromium supplementation to diets of pigs has been shown to increase the percentage of muscle by
7% and longissimus dorsi muscle area by 18%, while reducing 10th rib fat 20% and serum cholesterol 19%
(Page et al. 1993) when fed from 30 kg body weight until slaughter at 100 kg. Chromium response was specific for CrP. Other forms tested, including chromium chloride, were without effect. Similarly, porcine somatotropin
(pST) markedly improves growth performance and carcass composition of pigs
'Mention
INDEXING KEY WORDS:
of a trade name, proprietary
product or vendor does
not constitute a guarantee or warranty of the product by USDA or imply its approval to the exclusion of other products or vendors that also may be suitable.
2The costs of publication of this article were defrayed in pan by
•pigs •chromium •somatotropin •growth
the payment of page charges. This article must therefore be hereby marked "advertisement" in accordance with 18 USC section 1734 solely to indicate this fact.
3To whom correspondence should be addressed: USDA-ARS,
NANL, Bldg. 200, Room 201, BARC-East, 10300 Baltimore Blvd.,
Beltsville, MD 20705.
4Abbreviations used: CrP, chromium picolinate; IGFBP, insulinlike growth factor binding protein,- IGF-1, insulin-like growth factor
1; ppST, pituitary porcine somatotropin; pST, porcine somatotropin.
Chromium is an essential
Cited: Agricultural Research Council (1981| The Nutrient Requirements of Pigs Anderson, R. A. (1992| Chromium, glucose tolerance, and diabetes. Anderson, R. A. & Kozlovsky, A. S. (1985) Chromium intake, absorption, and excretion of subjects consuming self-selected Chemists (1970) Official M., McMurtry, J. P. & Wallace, J. C. (1990) Chicken insulin-like growth factor-I: amino acid sequence, radioimmunoassay, Coleman, M. E., Russell, L. & Etherton, T. D. (1992) Effects of porcine somatotropin (pST) on mRNA levels for GLUT4, IGF-1 Dunshea, F. R., Bauman, D. E., Boyd, R. D. & Bell, A. W. (1992) Temporal response of circulating metabolites and hormones Evans, G. W. (1989) The effect of chromium picolinate on insulin controlled parameters in humans Evans, G. W. & Bowman, T. D. (1992) Chromium picolinate in creases membrane fluidity and rate of insulin internalization Evock, C. M., Etherton, T. D., Chung, C. S. & Ivy, R. E. (1988) Pituitary porcine growth hormone (pGH) and a recombinant Folch, J., Lees, M. & Sloan Stanley, G. H. (1957) A simple method for the isolation and purification of total lipides from animal (1993) Effect of chromium picolinate on growth and serum and carcass traits of growing-finishing Roginski, E. E. & Mertz, W. (1969) Effects of chromium (ffl) sup plementation on glucose and amino acid metabolism in rats fed SAS Institute Inc. (1982) SAS User 's Guide: Statistics. SAS In stitute, Cary, NC. Steele, N. C., McMurtry, J. P. &. Rosebrough, R. W. (1985) Endo crine adaptations of periparturient swine to alteration of dietary Tollet, P., Enberg, B. & Mode, A. (1990) Growth hormone (GH) regulation of cytochrome P-450IIC12, insulin-like growth factorI (IGF-I), and GH receptor messenger RNA expression in primary Zenobi, P. D., Graf, S., Ursprung, H. & Froesch, E. R. (1992) Effects of insulin-like growth factor-I on glucose tolerance, insulin Downloaded from jn.nutrition.org by guest on October 1, 2011 brought about by CrP et al. 1992). In rats, somatotropin and insulin have