2. How does an organism’s genotype determine its phenotype? An organism’s genotype, its genetic makeup, is the sequence of nucleotide bases in its DNA. The phenotype, the organism’s physical traits, arises from the actions of a wide variety of proteins. Structural proteins help make up the body of an organism, and enzymes catalyze its metabolic activities. DNA specifies the synthesis of proteins. However, a gene does not build a protein directly, but rather dispatches instructions in the form of RNA, which in turn programs protein synthesis. This molecular chain of command is from DNA in the nucleus to RNA to protein synthesis in the cytoplasm. The two main stages are transcription, the transfer of genetic information from DNA into an RNA molecule, and translation, the transfer of the information from RNA into a protein.
2. How does an organism’s genotype determine its phenotype? An organism’s genotype, its genetic makeup, is the sequence of nucleotide bases in its DNA. The phenotype, the organism’s physical traits, arises from the actions of a wide variety of proteins. Structural proteins help make up the body of an organism, and enzymes catalyze its metabolic activities. DNA specifies the synthesis of proteins. However, a gene does not build a protein directly, but rather dispatches instructions in the form of RNA, which in turn programs protein synthesis. This molecular chain of command is from DNA in the nucleus to RNA to protein synthesis in the cytoplasm. The two main stages are transcription, the transfer of genetic information from DNA into an RNA molecule, and translation, the transfer of the information from RNA into a protein.