LSD is very potent: the effective dose is measured in micrograms (ug) -- however, the lethal dose is literally thousands of times that, making the drug essentially non-toxic. LSD is non-addictive, and there have been only a few cases of possible overdose where people ingested extremely large amounts of the drug (Alan et al., 1978; Griggs et al,. 1977). LSD can be administered a number of ways, the most common : orally though paper, sugar cubes, on a piece of gelatin, or by pill ; intravenously or intramu scularly. A standard dose with noticeable hallucinogenic effects is about 100-200 ug. The intensity of the trip is proportional to the size of the dose-- it is interesting to note, though, that the duration of the trip seems to stay the same at higher dos es (Freedman, 1984). Physical effects include drowsiness, dizziness, dilated pupils, numbness and tingling, weakness, tremors, and nausea. Transient abnormal thinking induced by LSD, such as a sense of omnipotence or a state of acute paranoia, can
References: 1) "Ethnopharmacology and Taxonomy of Mexican Psychodysleptic Plants" Jose Luis Diaz M.D. Journal of Psychedelic Drugs Vol. 11 (1-2) Jan-Jun 1979 2) "Erowid LSD vault" Website www.erowid.org/entheogens/lsd/lsd.shtml 3) "LSD Information" Website www.paranoia.com/drugs/psychedelics/lsd/" 4) "FAQ-LSD" (1995) from internet newsgroup: alt.drugs.psychedelics 5) "LSD: A total Study" Sankar (1975) 6) "Pharm Assist: The family guide to health and medicine" Interactive Multimedia CD ROM Software Marketing Corp. 1994 Phoenix AZ 7) "The LSD Story" Monroe, Judy, 1998 Current Health 2 1998 v24 n8 April-May p24(3)