REVIEW OF RELATED LITERATURE
This chapter presents the written and published local and foreign materials used by the researcher in gathering information about the Durio zibethinus Linn. and hepatoprotective property determination.
Family Name: Malvaceae
Scientific Name: Durio zibethinus Linn.
Common Name: Durian (Eng.) Duryan (Tag.)
Botanical Description: Durian is considered as “King of Tropical Fruit” due to its high nutritional status and with its appearance that resembles the thorny thrones of Asian kings (Subhadrabandhu and Ketsa, 2001). It is a highly prized fruit in Southeast Asian countries. Its production and export is dominated by Thailand, followed by Malaysia and Indonesia (Yahia, E.M., Singh S., 2009). Department …show more content…
Its rich pulp is eaten raw, cooked as a vegetable, frozen or dried for later use. Indonesians ferment the pulp for a side dish or mix the fleshy arils with rice and sugar to produce a local dish, lempong. The seeds can be boiled or roasted and used as confections (Orwa et al.2009). Most of the photochemicals are an integral part of the durian fruit and also being used in medicinal formulations. According to Faylon (2005), durian fruit, especially its flesh, is said to serve as a medication to eliminate parasitic worms. Moreover, in Malaya, decoction of durian leaves and fruits are applied to swellings and skin diseases while the ash of the burned rind is taken after …show more content…
Hepatic disease is a term that indicates damage to the cells, tissues, structure, or liver function, and this damage can be induced by biological factors (bacteria, virus, and parasites) and autoimmune diseases (immune hepatitis, primary biliary cirrhosis), as well as by the action of different chemicals, such as some drugs [high doses of paracetamol (PCM) and antitubercular drugs], toxic compounds [carbon tetrachloride (CCl4), thioacetamide, dimethylnitrosamine (DMN), D-galactosamine/lipopolysaccharide (GalN/LPS)], and unquestionably, excessive consumption of alcohol. (Astley SB, Elliott RM, Archer DB, Southon S.,