Esophageal Cancer Research Paper

Esophageal cancer is considered a serious malignancy with respect to prognosis and mortality rate. Account-ing for more than 400000 deaths worldwide in 2005[1].
Esophageal carcinoma is the eighth most common cancer, and the sixth most common cause of cancer related deaths worldwide with developing nations making up more than 80% of total cases and deaths[2]. Over 490000 new cases of esophageal cancer were reported in 2005.
While many other types of cancer are expected to decrease in incidence over the next 10 years by 2025 the prevalence of esophageal cancer is expected to increase by 140%[1]. According to the National Cancer Institute, in the United States there will be approximately 17990 new cases and 15210 deaths in 2013[3]. Despite many advances
The epidemiology of esophageal cancer in developed nations has dramatically changed over the past forty years. Forty years ago squamous cell carcinoma
(SCC) was responsible for greater than 90% of the cases of esophageal carcinoma in the United States.
Adenocarcinoma has now become the leading cause of esophageal cancer in the United States, representing 80% of cases[5]. In 1975 esophageal adenocarcinoma