BIO 120 – 01
Dr. Belinda Kadambi
October, 16 2014
Recombinant DNA Technology We’ve heard so many times the term “Biotechnology,” but what is Biotechnology? As we know at these days, biotechnology is not just a study area, it’s a group of technologies collected in one that share two main goals – improve our lives with working with living cells and molecules, and using organisms or their products for human purposes. But we want specific details, for example, what was the first step of Biotechnology in old days? From many years ago, biotechnology has been working with food, and the first step was a zymotechnology. This field was concentrated on brewing techniques, such as beer. In early 20th century, this field was expand to tackle larger industrial issues, and biotechnology with industrial fermentation, which is a metabolic process to make products useful for humans, get a chance to rise, but it was failed to progress because of the public resistance, political and economic issues, but biotechnology didn’t ceased to exist. There was the second move that would bring biotechnology on another level. It was the field of genetic engineering, also called genetic modification, which is a process of adding new DNA to an organism, and from where biotechnology started the intimate relationship between science and human society. One of the famous supporters of this new field was an American molecular biologist Joshua Lederberg. In 1972, Recombinant DNA started to exist because of the Paul Berg’s work with monkey virus SV40. When you take DNA molecules and join them together from different species that are inserted in one organism or host to make a new genetic combination, such as a creating of human insulin, it is a Recombinant DNA technology. First application of recombinant DNA technology I would like to say about is a transgenic and knockout animals for studying gene function. At