Extemporaneous Compounding
The Practicality of Extemporaneous Compounding in the 21st Century
Extemporaneous Compounding is the art or science of bringing together individual chemical components into a usable drug. It is considered to be a true pharmaceutical service which does not involve redistributing commercially manufactured drugs. It is used in cases where a drug is unavailable from pharmaceutical manufactures for individual patients. (Aquilina, 2013) The art of compounding medicinal medicines found its roots in the Western influence on pharmacy also referred to as, “Materia Medica” or substances used in the practice of ancient medicine. (Durgin & Hanan, 2009)
The usage of compounding became pervasive in the United States during the 19th century. 80 percent of all prescriptions were created through compounding up until the 1920’s where rapid advances in drug production lead to a sharp decline in its practice by 1950. The sudden surge of mass- produced drugs decreased compounded medications to less than one percent in the U.S. by 1970. The bulk of all prescribed drugs had fallen under the control of the pharmaceutical industry. By 1990, Extemporaneous Compounding quickly resurged due to the inability of mass-produced drugs to meet individual patient needs; and holistic …show more content…
In 2012 Ameridose LLC recalled all of it’s unexpired products in circulation, as a result of a CDC and FDA investigation of a fungal meningitis outbreak, due to contamination of their products earlier that same year. The testing of NECC products revealed a fungal bacteria present in the companies perservative-free sealed injectables betamethasone, triamcinolone and cardioplegia solutions. ( See
Extemporaneous Compounding is the art or science of bringing together individual chemical components into a usable drug. It is considered to be a true pharmaceutical service which does not involve redistributing commercially manufactured drugs. It is used in cases where a drug is unavailable from pharmaceutical manufactures for individual patients. (Aquilina, 2013) The art of compounding medicinal medicines found its roots in the Western influence on pharmacy also referred to as, “Materia Medica” or substances used in the practice of ancient medicine. (Durgin & Hanan, 2009)
The usage of compounding became pervasive in the United States during the 19th century. 80 percent of all prescriptions were created through compounding up until the 1920’s where rapid advances in drug production lead to a sharp decline in its practice by 1950. The sudden surge of mass- produced drugs decreased compounded medications to less than one percent in the U.S. by 1970. The bulk of all prescribed drugs had fallen under the control of the pharmaceutical industry. By 1990, Extemporaneous Compounding quickly resurged due to the inability of mass-produced drugs to meet individual patient needs; and holistic …show more content…
In 2012 Ameridose LLC recalled all of it’s unexpired products in circulation, as a result of a CDC and FDA investigation of a fungal meningitis outbreak, due to contamination of their products earlier that same year. The testing of NECC products revealed a fungal bacteria present in the companies perservative-free sealed injectables betamethasone, triamcinolone and cardioplegia solutions. ( See