Fibrodysplasia Ossificans Progressiva Research Paper

Fibrodysplasia Ossificans Progressiva Fibrodysplasia ossificans progressiva also known as F.O.P is a rare disorder that becomes noticeable in early childhood. This disorder includes the muscle and connective tissues like the tendons and ligaments. Those tissues are gradually replaced by bone, which in turn constrains movement. F.O.P occurs approx. one in two million people only a several hundred cases have been reported. Fibrodysplasia ossifican progressiva is a deadly disease that affects more than just the patient it affects the patients family, friends, relationships, and emotions. The most famous case known is Harry East Lack who died at the age of 39 from the disease. His short life is considered to be full for him to have F.O.P. This disease doesn’t have a discovery date but what I did discover was that the earliest known cases date back
Usually people with F.O.P have disfigured big toes they maybe short, curved inwards, and even bent. Things like this can be observed at birth. For babies if the malformed big toes don’t alarm, babies with F.O.P scoot on their bottoms instead of crawling on their hands and knees. This is because the joints in their backs and necks have not formed correctly. Most children don’t notice until they are about 10 this is because F.O.P usually occurs in the first two decades of someone’s life. Unfortunately there is no effective medical therapy but there are medicines like bisphosphonates and corticosteroids that helps with flare up which ease the pain of the condition. Lontophoresis along with steroids or acetic acid may help improve moving around with the condition. People who have F.O.P have to be very careful not to get hurt or have surgery for any major or minor reason. If any injury or surgery does occur more bones will grow in that area which in the long run will cause the person too not be able to move at