gene therapy article research 
http://www.nature.com/scitable/topicpage/controversies-in-treatment-approaches-gene-therapy-ivf-792
Historically, advances in science are typically made before society can conduct meaningful ethical and moral discussions about these advances. However, such discussions are crucial to setting policies that balance individual and public protections with the use of technology in medicine.
The in vitro fertilization (IVF) "miracle" of the late 1970s occurred five years before the polymerase chain reaction revolutionized the field of genetics, 18 years before the first bacterial genome was sequenced, and 26 years before completion of the human genome sequence. The intervening 30 years involved an explosion of knowledge of mammalian biology. Throughout this period, many members of the general public, especially those with incurable diseases or loved ones with incurable diseases, have been enthusiastic about the therapeutic application of these advances. Although curing disease is indeed one goal of genetic research, investigation of the overall safety of a treatment is also critical, as is consideration of the moral and ethical issues associated with a treatment. Although the first two tasks are reserved for scientists and clinical investigators, the latter is everyone's responsibility. This is particularly true when it comes to three recent "hot button" genetics-based therapies: gene therapy, stem cell therapy, and pharmacogenomics.
Gene Therapy
Human DNA is estimated to have approximately 12 million single nucleotide polymorphisms (SNPs) and thousands of copy number variants (CNVs), most of which are not harmful. However, genetic disorders do sometimes occur as a result of mutations that alter or inhibit protein function. Gene therapy focuses on correcting these mutated or defective genes by way of the following techniques:
Random insertion of a normal gene into the genome (most common technique)
Replacement of the abnormal gene with a normal one
Repair of the
Historically, advances in science are typically made before society can conduct meaningful ethical and moral discussions about these advances. However, such discussions are crucial to setting policies that balance individual and public protections with the use of technology in medicine.
The in vitro fertilization (IVF) "miracle" of the late 1970s occurred five years before the polymerase chain reaction revolutionized the field of genetics, 18 years before the first bacterial genome was sequenced, and 26 years before completion of the human genome sequence. The intervening 30 years involved an explosion of knowledge of mammalian biology. Throughout this period, many members of the general public, especially those with incurable diseases or loved ones with incurable diseases, have been enthusiastic about the therapeutic application of these advances. Although curing disease is indeed one goal of genetic research, investigation of the overall safety of a treatment is also critical, as is consideration of the moral and ethical issues associated with a treatment. Although the first two tasks are reserved for scientists and clinical investigators, the latter is everyone's responsibility. This is particularly true when it comes to three recent "hot button" genetics-based therapies: gene therapy, stem cell therapy, and pharmacogenomics.
Gene Therapy
Human DNA is estimated to have approximately 12 million single nucleotide polymorphisms (SNPs) and thousands of copy number variants (CNVs), most of which are not harmful. However, genetic disorders do sometimes occur as a result of mutations that alter or inhibit protein function. Gene therapy focuses on correcting these mutated or defective genes by way of the following techniques:
Random insertion of a normal gene into the genome (most common technique)
Replacement of the abnormal gene with a normal one
Repair of the