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Hematology

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Hematology
Intro to hematology:
1) Hematology is the study of the blood including what it looks like (morphology) and diseases.
2) The most frequently performed hematologic lab test is the CBC or complete blood count.
a) White Blood Cell Count (WBC) count
b) Red Blood Cell Count (RBS) count
c) Platelet count
d) Hemoglobin (Hgb)
e) Hematocrit (Hct)
f) Differential WBC count
g) RBC indices
3) Hemoglobin is a major component of RBC’s and it transports O2 to the tissues and carries CO2 from them back to the lungs.
a) The hemoglobin of Hgb test is used to measure, indirectly, the oxygen-carrying capacity of the blood.
b) The normal range for an adult female is 12-16 g/dL
c) The normal range for an adult male is 14 – 18 g/dL
d) It can be done on its own or as part of a CBC
4) Abnormal Hgb count
a) Anemia, especially iron deficiency anemia, hyperthyroidism, cirrhosis of the liver, severe hemorrhaging, as well as leukemia and Hodgkin’s disease result in a decreased Hgb.
b) COPD and Congestive heart failure can show an increase in Hgb levels.
5) The hematocrit (Hct) is a reliable method of measuring the percentage of formed elements to plasma in the blood.
a) In adult females the normal Hct range is 37 – 47% formed elements
b) In adult males the normal Hct range is 40-54% formed elements
c) The hematocrit divides the blood into three layers
i) The plasma, the buffy coat, and the packed red blood cells
d) The Plasma is the liquid portion of the blood
e) The Buffy coat is made up of White blood cells and Platelets and is in between
i) It looks like a white/gray fuzzy layer between the plasma and the RBC’s
f) The bottom is the dense red blood cells.
6) Abnormal Hct Levels:
a) Anemia is indicated by a low Hct
b) Polycythemia is indicated by a high Hct
i) Other factors can change the Hct such as level of hydration
7) The microhematocrit method
a) It is most often used in the POL
b) Blood is drawn directly from a skin-puncture (usually on the finger) and is

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