Inflammation Everywhere Case Study

Inflammation Everywhere:
Rising Rates of Autoimmune Disease and Allergies in Modern Society
In his book, The Epidemic of Absence, Moises Velasquez-Manoff states in a 2009 study found that the prevalence of celiac disease increased fourfold after the year 1950, in addition to diabetes and multiple sclerosis affecting three times the number of citizens around the globe (7). Inflammatory disease occurrences, such as allergies and autoimmune disorders, have grown drastically within the western-cultured society in the past century. Today, approximately eighty disorders affect twenty-three million Americans. According to Benroya Research Institute, autoimmune disorders cause the body’s own immune system, such as white blood cells and macrophages,
Maslowski and Mackay’s research in "Diet, Gut Microbiota and Immune Responses" shows children raised in cities away from the rural country suffer from increased sensitivity to common allergens. They found the more kids help out on the farm, the less likely their defensive cells are to mistake a common allergen for an intrusive invader. This idea reinforces the hygiene theory, which states that the world’s response to the germ-free environment impacts autoimmune disease and allergies in a negative way. Dr. David Brady, an associate professor of clinical science at the University of Bridgeport, explains his reasoning of the necessity of contact with some common allergens and diseases by saying, “This ‘clean new world’ has likely resulted in a lack of adequate sampling of our environment, including exposure to all of the microbes that we share our planet with, particularly while we are young and our immune systems are developing the delicate balance between adequate defense and tolerance.” Moises Velasquez-Manoff adds that a child’s immunity and allergic reaction systems depend on their acquaintance with or actual ingestion of the proteins within allergens. Once thought to aid in preventing issues, doctors told parents to refrain from
"Autoimmune Disease: A Modern Epidemic?." Townsend Letter, no. 347, June 2012, pp. 44-50. EBS.COhost, www.statelib.lib.in.us/inspire/authenticate-eds.asp?url=http%3a%2f%2fsearch.ebscohost.com%2flogin.aspx%3fdirect%3dtrue%26AuthType%3dcookie%2cgeo%2curl%2cip%26geocustid%3ds8475741%26db%3dawh%26AN%3d79367189%26site%3deds-live%26scope%3dsite. Accessed on 1 February 2018
“Disease Information.” Benaroya Research Institute, 27 Feb. 2017, www.benaroyaresearch.org/what-is-bri/disease-information. Accessed on 28 February 2017
Maslowski, Kendle M. and Charles R. Mackay. "Diet, Gut Microbiota and Immune Responses"
Nature Immunology, no. 1, 2011, p. 5. EBSCOhost, www.statelib.lib.in.us/inspire/authenticate-eds.asp?url=http%3a%2f%2fsearch.ebscohost.com%2flogin.aspx%3fdirect%3dtrue%26AuthType%3dcookie%2cgeo%2curl%2cip%26geocustid%3ds8475741%26db%3dedsgsc%26AN%3dedsgcl.245483263%26site%3deds-live%26scope%3dsite. Accessed on 1 February 2018
Myles, Ian A. “Fast Food Fever: Reviewing the Impacts of the Western Diet on Immunity.”BioMed Central, Nutrition Journal, 17 June 2014, www.ncbi.nlm.nih.gov/pmc/articles/PMC4074336/. Accessed on 23 February 2018
Velasquez-Manoff, Moises. An Epidemic of Absence. Simon & Schuster, Inc,