Leomi The Struggle With Leukemia
THE STRUGGLE WITH LEUKEMIA This essay is going to be about the factors, symptoms, and the medicine you take for the cancer Leukemia. If you don’t know much about Leukemia then stick around and I’ll tell you all about it. The first topic is how it forms, or the risk factors. Leukemia is any of several cancers of bone marrow. It prevents red blood cells, white blood cells, and platelets from forming correctly. It results in anemia, which is the increased ability to get an infection and impaired blood clotting. There are several types of leukemia. Some types are; Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Acute Non-Lymphocytic Leukemia, and Agnogenic Myeloid Metaplasia. Acute Lymphoblastic Leukemia affects all lymphoid cells
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and it grows very quickly. Acute Myeloid Leukemia is a rapidly progressing cancer of blood affecting immature cells of the bone marrow. Acute Non-Lymphocytic Leukemia is a form of Acute Myeloid Leukemia (Leukemia). There are two forms of all of the leukemia types listed above. The two types are chronic and acute. Chronic Leukemia develops slowly. Acute leukemia develops more rapidly and is harder to treat. In Chronic Leukemia the white blood cells appear more mature and resemble normal white blood cells. At early stages the cells can function normally. Chronic Lymphocytic Leukemia is the most common in adults. The disease can take as long as 10 years to develop. It usually changes within several years into acute leukemia. When it reaches that point it is resistant to most treatments. Acute Lymphoid Leukemia is the most common cancer among children. About 70% that have (ALL) can be cured with certain treatments (About Diseases). Acute Myeloid usually strikes adults, but in some certain cases children can get it. Amyloidosis isn’t a specific disease but it is the term of a group of conditions. Amyloidosis is an abnormal substance called amyloid is deposited throughout the body. Amyloid is produced by plasma cells and amyloidosis may occur in association with multiple myeloma (Leukemia WB). The Ph chromosome is an abnormality that occurs when a piece of chromosome 22 breaks off and a piece of chromosome 9 breaks off; they both of connect. The breaks in both of the chromosomes cause the BCR and ABL genes. When they combine together they combine the cancer gene. It is called t(9;22). It is carried out in the chromosome level. The switch leads to procreation of enzymes that trigger cell growth. The link found between them was discovered around 1960. The American Cancer Society said there was about 5,050 CML incidents in the U.S. in 2009. CML makes up about 10 – 25% of all types of Leukemia. The average age of being diagnosed is 67 years old. CML is like silent Leukemia. It can be in your system for years and not be noticed. Then all of a sudden it can be found several years later. Here are the risk factors: gender, age, family history, and genetic diseases. Gender- men are more likely to develop CML, CLL, and AML than women. Age- the risk of most leukemias, typically increase with age. Family history- most leukemias don’t have family link. But first degree relatives of CLL patients or if they have a twin with AML or ALL can put you at risk of having it. Genetic Diseases- Certain genetic abnormalities like Down Syndrome. Many play a role in the development of leukemia. CLL is the most common in adults. The disease can take as long as 10 years to develop. It typically changes within several years into Acute Leukemia. It is then resistant to most treatments. CML occurs mostly in adults. The cause of most Leukemia is unknown. Possible causes could be: genetic abnormalities and exposure to radiation. Chronic Leukemia stages in the Rai System. They are classified by 3 main factors: the number of Lymphocytesin in blood, enlarged organs, past blood disorders, their lifestyle, smoking habits, exposure to high radiation, and long-term exposure to pesticides. There are many other risk factors as well as the ones listed in the previous sentence. Acute types of Leukemia are staged based on the type of cell involved and how they look. It is called the French-American-British Classification System. Lymphocytic Leukemias occur in a type of white blood cells called Lymphocytes. White blood cell count at diagnosis can be used to help stage the Leukemia. Staging for Myeloid Leukemias is based on the number of Myeloblasts found in bone marrow or blood. Factors affecting the stages are as follows: white blood cell or platelet count, age, history, or prior blood disorders, chromosome mutations, abnormalities, bone damage, and enlarged organs. It may also be several of those factors combined. All of those factors and different types of cancer have to have treatment options. The next paragraph will explain the different types of treatment options. This paragraph is about the different types of treatment options for treating the many types of Leukemia. Leukemia is a dangerous cancer; which most cancers are. The treatment options are very slim. There are tests that are used to examine the bone marrow and the blood. Certain factors affect the chance of recovery and treatment options. The bone is made up of compact bone, spongy bone, and bone marrow. Compact bone makes up the outer layer of the bone. Spongy bone is found mostly at the ends of the bones. The spongy bone contains red bone marrow. Bone marrow is found in the center of the bone itself. The bone marrow has many blood vessels. There are two types of bone marrow; red and yellow. Red marrow contains blood stem cells that can become red blood cells, white blood cells, and platelets. Yellow marrow is made of mostly fat. Normally bone marrow makes blood stem cells. They become mature blood cells over time. A blood stem cell may become a myeloid stem cell or a lymphoid stem cell. Red blood cells carry oxygen and other substances to the body. Platelets that form blood clots help to stop bleeding. Granulocytes is another term for white blood cells. The white blood cells fight infection and disease. Granulocytes in CML are abnormal and do not become healthy white blood cells. They build up in the blood and become bone marrow. When that happens scientists have to create medicines for the specific characteristics of each type of cancer (Understanding). There are two types of medications that are most commonly known. The first is Sprycel. The second is Gleevec. Sprycel is a type of radiation pill. You take it once every night before bed. The pill causes you to be nauseous and light headed. It causes your body to be weak and sometimes hard to function. Sprycel is a dangerous toxic chemical that should only be used by someone that it has been prescribed to. It is not known is Sprycel is safe for children younger than 18 years of age. You are not supposed to drink grapefruit juice if you are taking Sprycel (Understanding). Sprycel can cause Pulmonary Arterial Hypertension. It can also cause severe skin reactions. It may also cause Lysis Syndrome. LS is a fast breakdown of cancer cells. It may cause kidney failure and an abnormal heartbeat. Gleevec blocks the action of enzymes (Leukemia WB). It is only available by prescription. It is for newly diagnosed adults in the chronic stage of Myeloid Leukemia. Here are some precautions if you are taking it and don’t want any harm done to anything. If a woman is pregnant she should not take it because it could cause harm to the unborn baby, such as birth defects. Women who breastfeed can cause the baby to form abnormalities. Gleevec can cause your body to retain too much water. It may also cause severe liver damage. One factor that can occur is growth retardation, the slowing of growth hormones (Gleevec). Leukemia is not a fun thing to have.
People with leukemia lose their hair, throw up a lot, they’re weak, and they can’t do the things they were once able to do. Leukemia is a cancer that can be easily cured. Sometimes if it isn’t noticed at the right time it can be fatal. Leukemia has different stages for the seriousness of how the cancer has spread. CML is a cancer that once it reaches the third stage it cannot be cured. They can give medicines out to help slow the symptoms down but in all it will not make it go away. You can get a Bone Marrow Transplant, do Chemotherapy, Radiation Therapy, Biological Therapy, Targeted Therapy, and a Stem Cell Transplant. Chemotherapy is a major form of treatment for Leukemia. That certain kind of procedure uses chemicals to kill Leukemia cells. You may receive single doses, such as a pill every night. It may be a combination of drugs as well. The last option is to have it injected into your veins. Radiation Therapy uses x-rays or other high-energy beams to damage Leukemia cells. It stops the Leukemia cells growth. When doing Radiation Therapy you lie on a table while a large white machine moves around you. It directs the radiation to certain points of your body. Biological Therapy uses treatments to help find and attack the Leukemia cells. Targeted Therapy uses drugs to attack specific vulnerabilities within the cancer cells. Gleevec is a type of medicine used in Targeted Therapy. It stops the action of protein within the Leukemia cells. A Stem Cell Transplant is a procedure that replaces the diseased bone marrow and replaces it with new. Before they start the transplant they give you high doses of radiation and chemotherapy to destroy the diseased bone marrow. If you want to be a donor then you have to be an exact match to the patient. You could be a brother, sister, or even a parent of the patient. Depending on what is contained in your bone marrow and blood cells
(Mayo).
CML monitoring relies on bone marrow cytogenetics. . It goes through the first 12-18 months. Proteins in Leukemia cells have high sensitivity. Freshly collected blood samples are gotten from patients visiting outpatient clinics from centers that participate in the Sicily and Calabria CML Regional ENterprise (SCREEN). It is a network that has the Declaration of Helsinki. Samples are looked at in the Cosenza laboratory and processed there as well. Bone marrow aspiration and biops are tests that are run at the same time. The samples are taken from the pelvic bone for both testing methods. Aspiration can be taken from the breast bone. They lay you on a table, clean the area, and stick a hollow needle deep inside your hip/pelvic bone. A syringe is then used to take a small sample of liquid bone marrow. Most people still feel brief pain after the procedures. A bone marrow biopsy is done after the Aspiration. A small piece of bone and marrow is removed for testing. When done taking out the small pieces, pressure is applied to stop the bleeding. They then look at it under a microscope and send it to the lab to be tested. A complete blood cart is then processed (Recchia), (Treating), (Leukemia WB). Leukemia is a hard cancerous disease to have. Imagine living in a cancer patients shoes. The cost of their medicine is outrageous, their hair falls out, their bodies are damaged, and it could be fatal. Being a cancer patient is hard work. If you think your life is hard, try dealing with chemotherapy and radiation. This research paper was about the factors, symptoms, and the medicine taken for Leukemia. If you want more information on cancer patients with Leukemia you can go to the website www.cancercenter.org and they will have all of the information you need.
and it grows very quickly. Acute Myeloid Leukemia is a rapidly progressing cancer of blood affecting immature cells of the bone marrow. Acute Non-Lymphocytic Leukemia is a form of Acute Myeloid Leukemia (Leukemia). There are two forms of all of the leukemia types listed above. The two types are chronic and acute. Chronic Leukemia develops slowly. Acute leukemia develops more rapidly and is harder to treat. In Chronic Leukemia the white blood cells appear more mature and resemble normal white blood cells. At early stages the cells can function normally. Chronic Lymphocytic Leukemia is the most common in adults. The disease can take as long as 10 years to develop. It usually changes within several years into acute leukemia. When it reaches that point it is resistant to most treatments. Acute Lymphoid Leukemia is the most common cancer among children. About 70% that have (ALL) can be cured with certain treatments (About Diseases). Acute Myeloid usually strikes adults, but in some certain cases children can get it. Amyloidosis isn’t a specific disease but it is the term of a group of conditions. Amyloidosis is an abnormal substance called amyloid is deposited throughout the body. Amyloid is produced by plasma cells and amyloidosis may occur in association with multiple myeloma (Leukemia WB). The Ph chromosome is an abnormality that occurs when a piece of chromosome 22 breaks off and a piece of chromosome 9 breaks off; they both of connect. The breaks in both of the chromosomes cause the BCR and ABL genes. When they combine together they combine the cancer gene. It is called t(9;22). It is carried out in the chromosome level. The switch leads to procreation of enzymes that trigger cell growth. The link found between them was discovered around 1960. The American Cancer Society said there was about 5,050 CML incidents in the U.S. in 2009. CML makes up about 10 – 25% of all types of Leukemia. The average age of being diagnosed is 67 years old. CML is like silent Leukemia. It can be in your system for years and not be noticed. Then all of a sudden it can be found several years later. Here are the risk factors: gender, age, family history, and genetic diseases. Gender- men are more likely to develop CML, CLL, and AML than women. Age- the risk of most leukemias, typically increase with age. Family history- most leukemias don’t have family link. But first degree relatives of CLL patients or if they have a twin with AML or ALL can put you at risk of having it. Genetic Diseases- Certain genetic abnormalities like Down Syndrome. Many play a role in the development of leukemia. CLL is the most common in adults. The disease can take as long as 10 years to develop. It typically changes within several years into Acute Leukemia. It is then resistant to most treatments. CML occurs mostly in adults. The cause of most Leukemia is unknown. Possible causes could be: genetic abnormalities and exposure to radiation. Chronic Leukemia stages in the Rai System. They are classified by 3 main factors: the number of Lymphocytesin in blood, enlarged organs, past blood disorders, their lifestyle, smoking habits, exposure to high radiation, and long-term exposure to pesticides. There are many other risk factors as well as the ones listed in the previous sentence. Acute types of Leukemia are staged based on the type of cell involved and how they look. It is called the French-American-British Classification System. Lymphocytic Leukemias occur in a type of white blood cells called Lymphocytes. White blood cell count at diagnosis can be used to help stage the Leukemia. Staging for Myeloid Leukemias is based on the number of Myeloblasts found in bone marrow or blood. Factors affecting the stages are as follows: white blood cell or platelet count, age, history, or prior blood disorders, chromosome mutations, abnormalities, bone damage, and enlarged organs. It may also be several of those factors combined. All of those factors and different types of cancer have to have treatment options. The next paragraph will explain the different types of treatment options. This paragraph is about the different types of treatment options for treating the many types of Leukemia. Leukemia is a dangerous cancer; which most cancers are. The treatment options are very slim. There are tests that are used to examine the bone marrow and the blood. Certain factors affect the chance of recovery and treatment options. The bone is made up of compact bone, spongy bone, and bone marrow. Compact bone makes up the outer layer of the bone. Spongy bone is found mostly at the ends of the bones. The spongy bone contains red bone marrow. Bone marrow is found in the center of the bone itself. The bone marrow has many blood vessels. There are two types of bone marrow; red and yellow. Red marrow contains blood stem cells that can become red blood cells, white blood cells, and platelets. Yellow marrow is made of mostly fat. Normally bone marrow makes blood stem cells. They become mature blood cells over time. A blood stem cell may become a myeloid stem cell or a lymphoid stem cell. Red blood cells carry oxygen and other substances to the body. Platelets that form blood clots help to stop bleeding. Granulocytes is another term for white blood cells. The white blood cells fight infection and disease. Granulocytes in CML are abnormal and do not become healthy white blood cells. They build up in the blood and become bone marrow. When that happens scientists have to create medicines for the specific characteristics of each type of cancer (Understanding). There are two types of medications that are most commonly known. The first is Sprycel. The second is Gleevec. Sprycel is a type of radiation pill. You take it once every night before bed. The pill causes you to be nauseous and light headed. It causes your body to be weak and sometimes hard to function. Sprycel is a dangerous toxic chemical that should only be used by someone that it has been prescribed to. It is not known is Sprycel is safe for children younger than 18 years of age. You are not supposed to drink grapefruit juice if you are taking Sprycel (Understanding). Sprycel can cause Pulmonary Arterial Hypertension. It can also cause severe skin reactions. It may also cause Lysis Syndrome. LS is a fast breakdown of cancer cells. It may cause kidney failure and an abnormal heartbeat. Gleevec blocks the action of enzymes (Leukemia WB). It is only available by prescription. It is for newly diagnosed adults in the chronic stage of Myeloid Leukemia. Here are some precautions if you are taking it and don’t want any harm done to anything. If a woman is pregnant she should not take it because it could cause harm to the unborn baby, such as birth defects. Women who breastfeed can cause the baby to form abnormalities. Gleevec can cause your body to retain too much water. It may also cause severe liver damage. One factor that can occur is growth retardation, the slowing of growth hormones (Gleevec). Leukemia is not a fun thing to have.
People with leukemia lose their hair, throw up a lot, they’re weak, and they can’t do the things they were once able to do. Leukemia is a cancer that can be easily cured. Sometimes if it isn’t noticed at the right time it can be fatal. Leukemia has different stages for the seriousness of how the cancer has spread. CML is a cancer that once it reaches the third stage it cannot be cured. They can give medicines out to help slow the symptoms down but in all it will not make it go away. You can get a Bone Marrow Transplant, do Chemotherapy, Radiation Therapy, Biological Therapy, Targeted Therapy, and a Stem Cell Transplant. Chemotherapy is a major form of treatment for Leukemia. That certain kind of procedure uses chemicals to kill Leukemia cells. You may receive single doses, such as a pill every night. It may be a combination of drugs as well. The last option is to have it injected into your veins. Radiation Therapy uses x-rays or other high-energy beams to damage Leukemia cells. It stops the Leukemia cells growth. When doing Radiation Therapy you lie on a table while a large white machine moves around you. It directs the radiation to certain points of your body. Biological Therapy uses treatments to help find and attack the Leukemia cells. Targeted Therapy uses drugs to attack specific vulnerabilities within the cancer cells. Gleevec is a type of medicine used in Targeted Therapy. It stops the action of protein within the Leukemia cells. A Stem Cell Transplant is a procedure that replaces the diseased bone marrow and replaces it with new. Before they start the transplant they give you high doses of radiation and chemotherapy to destroy the diseased bone marrow. If you want to be a donor then you have to be an exact match to the patient. You could be a brother, sister, or even a parent of the patient. Depending on what is contained in your bone marrow and blood cells
(Mayo).
CML monitoring relies on bone marrow cytogenetics. . It goes through the first 12-18 months. Proteins in Leukemia cells have high sensitivity. Freshly collected blood samples are gotten from patients visiting outpatient clinics from centers that participate in the Sicily and Calabria CML Regional ENterprise (SCREEN). It is a network that has the Declaration of Helsinki. Samples are looked at in the Cosenza laboratory and processed there as well. Bone marrow aspiration and biops are tests that are run at the same time. The samples are taken from the pelvic bone for both testing methods. Aspiration can be taken from the breast bone. They lay you on a table, clean the area, and stick a hollow needle deep inside your hip/pelvic bone. A syringe is then used to take a small sample of liquid bone marrow. Most people still feel brief pain after the procedures. A bone marrow biopsy is done after the Aspiration. A small piece of bone and marrow is removed for testing. When done taking out the small pieces, pressure is applied to stop the bleeding. They then look at it under a microscope and send it to the lab to be tested. A complete blood cart is then processed (Recchia), (Treating), (Leukemia WB). Leukemia is a hard cancerous disease to have. Imagine living in a cancer patients shoes. The cost of their medicine is outrageous, their hair falls out, their bodies are damaged, and it could be fatal. Being a cancer patient is hard work. If you think your life is hard, try dealing with chemotherapy and radiation. This research paper was about the factors, symptoms, and the medicine taken for Leukemia. If you want more information on cancer patients with Leukemia you can go to the website www.cancercenter.org and they will have all of the information you need.