There is no actual direct evidence against an afterlife - only arguments refuting the specific examples of evidence for life after death as not being sufficient proof. Although it can easily be argued that not having direct knowledge of an afterlife constitutes evidence against life after death. Life after death cannot be disproven; only the evidence in its favour can be scrutinized and rational non-believers are left to make the conclusion that life after death cannot be proven.
∙ It is hard to imagine any species (ie. mankind) would reach such a high level of consciousness of our own existence if it were all to end with this life. There is no evolutionary advantage or biological need for this. For a mortal life here on earth, the human mind is much more advanced than necessary.
Possibly we have reached such a state of consciousness, because there is a continuum to this life after this one ends? Just being conscious of our existence suggests that there may be an afterlife. Why else would we be aware of our mortality or be concerned with life after death? Possibly we can only fathom we could cease to exist because we never will cease to exist? In fact, awareness of our mortality or immortality and what it means goes beyond the awareness you exist (consciousness). Having a soul can explain consciousness, but if we do not possess souls, then how do we account for consciousness?
If it so happens that ones existence can end at any time and is not everlasting, it makes ones existence pointless in