Preview

Merck Vioxx Paper

Good Essays
Open Document
Open Document
710 Words
Grammar
Grammar
Plagiarism
Plagiarism
Writing
Writing
Score
Score
Merck Vioxx Paper
In the year 2000, Merck produced a controversial product called Vioxx. Four years later it gained worldwide attention because of the drug’s potential cardiovascular risks. This was detrimental to the company’s reputation because it was alleged Merck knowingly distributed Vioxx despite its risk. Both Barbara Martinez and Anne W. Mathews of the Wall Street Journal wrote articles into the investigation of Vioxx. Their article suggests Merck knew the dangers of Vioxx at an early stage of its clinical trials. This information is derived from Edward Scolnick’s email to colleagues, that “the cardiovascular events are clearly there" and called it a "shame."He compared Vioxx to other drugs with known side effects and wrote, “there is always a hazard” (Martinez, Mathews, 2004). Further complications arose for Merck when Richard Horton from the Lance published an article about Merck’s marketing document labeled “Dodge Ball Vioxx” (Horton 2004). This document was intended for the company’s sales representatives which, discussed how to respond to questions about Vioxx. In order to refute the arguments brought up by the Wall Street journalists and Richard Horton, Merck published their own Open Letters. In the Open Letters, Merck used three strategies to try and counter the negative press over its handling of Vioxx. Their persuasive strategies focused on the company’s good sense and knowledge, good moral character, and good will. Merck’s first strategy points to their good sense and knowledge of the medicine which serves to regain credibility and to establish the company as a professional organization. In the rebuttal they specifically point out Vioxx was studied both before and after getting FDA approval. By taking this approach, the company attempts to build consumer confidence and show its knowledge of their product. In addition, Merck attempts to build integrity among its employees by pointing out their policies and formal training programs. Next, Merck


Cited: Martinez, M.B. , Matthews, M.A., 2004, Warning Signs: E-Mails Suggest Merck Knew Vioxx 's Dangers at Early Stage, Wall Street Journal,6. Horton, H.R., 2004, Vioxx, the implosion of Merck, and aftershocks at the FDA, The Lance, Volume 364, 1995.

You May Also Find These Documents Helpful

  • Good Essays

    Merck and Vioxx

    • 972 Words
    • 4 Pages

    In May of 1999, the FDA approved the use of rofecoxib. Marketed under the name of Vioxx, rofecoxib was manufactured and distributed by Merck, a large pharmaceutical company. Doctors prescribed the drug as a non-steroidal anti-inflammatory and prescription painkiller. Five years after its release, rofecoxib was withdrawn because of a study that showed the drug more than doubled the risk of heart attack or stroke. Because of Merck’s ongoing and increasing knowledge of the dangerous effects of the drug while continuing to distribute rofecoxib, Merck should be held accountable for acting unethically.…

    • 972 Words
    • 4 Pages
    Good Essays
  • Powerful Essays

    The Medicines Company

    • 868 Words
    • 5 Pages

    The Medicines Company Case Write-Up: Terence Cho, Felipe Duarte, Aleks Loiko, Robert Shaw, and James Wang…

    • 868 Words
    • 5 Pages
    Powerful Essays
  • Good Essays

    RES 351 Wk 1

    • 793 Words
    • 2 Pages

    There were many injured parties in the case of GSK. To start the company was a huge injured party, as well as the company that did the clinical trials for them. The researchers were put under pressure by investigations that followed the discovery of GSK’s false reports. The negative attention alone can affect the trust others put in their research.…

    • 793 Words
    • 2 Pages
    Good Essays
  • Good Essays

    However, several studies have questioned the cardiovascular safety of Vioxx. The manufacture of Vioxx has announced a voluntary withdrawal of the drug from the U.S. and worldwide market in September 30, 2004. After the company’s own 3 year study was stopped. Two million Americans were taking Vioxx when it was pulled and Merck had said that approximately 20 million people in the U.S. have used the drug. This withdrawal was due to some safety concerns of an increased risk of cardiovascular events, including heart attacks and strokes in patients taking Vioxx during the first 18 months. In the 5 years that Vioxx was on the market over 88,000 and 140,000 cases of heart disease were reported, of those cases 30 to 40 percent were fatal. The records indicate that the action of both Merck and the US Food and Drug Administration (FDA) found nearly 30,000 excess cases of heart attacks and sudden cardiac deaths that resulted from the use of this drug between 1999 and 2003. Over 300 lawsuits have been filed against Merck, and was expected that thousand more will…

    • 830 Words
    • 4 Pages
    Good Essays
  • Better Essays

    Res 351 week 2

    • 985 Words
    • 3 Pages

    Merck & Co. marketed a drug called Vioxx. The drug was said to have less gastrointestinal problems than its competition – Naproxen. However, Vioxx had considerably more side effects including; heart attacks and strokes (Vershoor,C.C, 2006). Merck and Co. were accused of several unethical acts, therefore, the drugs were pulled from the market in September 2004. Unfortunately, not before 100 million prescriptions were filled. Merck & Co. was also accused of misrepresenting or concealing of study results to doctors. The New England Journal of Medicine reported that previous studies of three patients had been withheld. All three patients suffered heart attacks when taking Vioxx. Sales reps for Merck & Co. were trained to use subliminal selling tactics. Additionally, Merck & Co. only chose biased speakers of their products at educational…

    • 985 Words
    • 3 Pages
    Better Essays
  • Good Essays

    Unit 1 Homework

    • 900 Words
    • 3 Pages

    1, What would be your view of what Merck has done: economically, legally, and ethically? Assume that all this has occurred before September 2004, when the senior executives at Merck removed Vioxx from the market, and while the risks of Vioxx were still not public knowledge. Would you approve, or disapprove, of the continued sale of the drug by your firm?…

    • 900 Words
    • 3 Pages
    Good Essays
  • Good Essays

    Brain Gym Analysis

    • 1243 Words
    • 5 Pages

    Drug companies distribute and promote their changed results in academic journals, tricking very nearly anybody into putting their dangerous and inaccurately tested drugs on the market. In duplicate publication if a drug company gets a better result, they will republish their findings in slightly different ways and in multiple academic sources. “One drug called ondansetron managed to overestimate the drug's effect by 23% using this method” (Goldacre, 2011, pp.164-165). Side effects usually happen and can often be severe. Harmful side effects and their negative results, when known, can discourage medicine buyers. Drug companies can muffle the negative reactions by contrasting them with horrible symptoms that another, comparative medication may have. According to drugwatch.com, one type 2 diabetes drug, Actos, which was prescribed 10 million times and FDA approved, increases the chance of bladder cancer by 40% and causes an increased risk of heart failure. Vioxx a painkiller that was approved in 1999 by the FDA was studied in a trial against an older drug, naproxen, to compare the different side effects much money was invested in the trial, and the pending…

    • 1243 Words
    • 5 Pages
    Good Essays
  • Satisfactory Essays

    Questions 6

    • 535 Words
    • 2 Pages

    References: Williams, S.J, Torrens, P.R., (2008). Chapter 11: The Pharmaceutical Industry. Introduction to Health Services (7th ed).…

    • 535 Words
    • 2 Pages
    Satisfactory Essays
  • Good Essays

    As a result of worldwide withdrawal of Vioxx, Merck faced a serious public relations crisis in the fall of 2004. Pharmaceutical giant’s officials were forced to defend company’s actions, its motivation for those actions, and its reputation after several articles, negatively reflecting on Merck’s behavior handling the Vioxx case, had been published. As an initial response to Vioxx crisis, the company released “An Open Letter from Merck” and “For 100 years, patients first” in attempt at a positive rebuttal. These open letters try to counter the negative press by using the following three strategies: utilization of Aristotelian view of rhetoric as a persuasion technique by building ethos with the readers; precise wording choices that emphasize…

    • 866 Words
    • 4 Pages
    Good Essays
  • Better Essays

    As the communication coordinator for this national drug manufacturer, we will need to address the issue at hand and figure out the best way to handle the negative publicity one of our medications has caused. Unfortunately, the local news is already making things more difficult for us by alleging that a well-known public figure is among those suffering adverse effects from this medication. We will need to decide how to properly address the public that will ensure no loss in business or investors. In this meeting, we will need to determine the best communication tactic to get this situation under control.…

    • 1068 Words
    • 5 Pages
    Better Essays
  • Better Essays

    Reality of Vaccinations

    • 1907 Words
    • 55 Pages

    Mercola, Dr. J. "Flacking for Big Pharma." Mercola.com. N.p., 12 Feb. 2013. Web. 28 Apr. 2013. <http://articles.mercola.com/sites/articles/archive/2013/02/14/big-pharma-tricks.aspx>.…

    • 1907 Words
    • 55 Pages
    Better Essays
  • Good Essays

    What Is Biased Research

    • 615 Words
    • 3 Pages

    Consequently, happened that Avandia drug had influenced documentation on the dangerous side effects that remained unknown. One assumption is an individual taking the drug that the research had gone through a rigorous test. The FDA learned about the dangerous side effects that caused heart attacks and required that the GlaxoSmithKline drug maker of Avandia drug to perform a study to determine the possible dangers. Although, GlaxoSmithKline drug research denied information from the FDA. The FDA started bias restriction research that drug manufacturers would have to release publications of data showing medication side effects. Therefore, as a consumer, it's hard to trust the result of the pharmaceutical making companies, research that is bias instead of truth and This doesn’t happen because it is challenging for the consumer to believe them. However, GlaxoSmithKline continues to hide data and remains biased over incomplete information that sanctions profit without concern for the medical health of individuals. Therefore, the pharmaceutical researchers remain biased because they just did not conduct scientific analyzing of rigorous testing and publishing the full…

    • 615 Words
    • 3 Pages
    Good Essays
  • Good Essays

    Merck Case

    • 587 Words
    • 4 Pages

    Merck had a 14% increase in sales between 1997 and 1998 and 22% increase in sales from 1998 – 1999, and a 13% annual increase in earnings over the same period. Merck’s business strategy consists of two parts: (1) developing and marketing new drugs through internal research, and (2) developing partnerships with smaller biotechnology companies. Since 1995, Merck had launched 15 new products that earned $5.9 billion on sales of $32.7 billion. Furthermore, Merck may agree to license new drugs from other firms and with its larger capital and greater assets, can assume the risk of submitting the drug through various regulatory approval phases. If the drug becomes profitable, Merck can earn significant cash flows while paying a royalty to the licensor. However, most important is the option that Merck has in deciding when to abandon or continue on this project (deferability or optionality). If Merck reaches a point when its expected NPV is negative, it can simply abandon the project. As a licensee, Merck can allow smaller biotechnology firms to focus on research and development. These smaller firms often have smaller budgets and are not financially or personnel equipped to handle the costly and long FDA approval process, and the subsequent marketing, distribution, and sales of new drugs. This task is better suited for a larger company, such as Merck, which has more resources and money.…

    • 587 Words
    • 4 Pages
    Good Essays
  • Good Essays

    Biomax Case Summary

    • 1049 Words
    • 5 Pages

    The Company's primary strategy is to get those prescriptions surrendered by other pharmaceutical organizations. Despite the fact that the Company has received 4 standards to screen among the competitors, in any case it confronts the potential danger of disappointment. Drug organizations relinquished these items for a mixture of great reason including security, viability and benefit potential. Why does the Medicines Company have the Golden Finger? There is no such ensure that items which consent to the 4 criteria will end up being a blockbuster product. The Company seems to fail to offer an agreeable advertising arrangement for Angiomax and other future medications that are coming to company regarding to FDA. So we should stay sensible about…

    • 1049 Words
    • 5 Pages
    Good Essays
  • Powerful Essays

    Sanofi-Aventis Acquisition

    • 5913 Words
    • 19 Pages

    Bibliography: Cleaves, K., Thayer A., (August 2004). Warning, merge with care: Sanofi-Aventis. Modern Drug Discovery. Retreived on June 6, 2014 from http://pubs.acs.org/subscribe/archive/mdd/v07/i08/pdf/804business2.pdf…

    • 5913 Words
    • 19 Pages
    Powerful Essays

Related Topics