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Molecular Biology

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Molecular Biology
1859
Charles Darwin published the "On the Origin of Species", introducing that genetic evolution allowed adaptation over time to produce organisms best suited to the environment

1865
Gregor Mendel investigated "traits" passed from parents to prodigy and coined the terms dominant and recessive traits

1869
Johann Meisher isolated DNA from the nuclei of white blood cells

1875
Charles Darwin introduced "gemmules" as mechanism of inheritance

1902
Walter Sutton created term "gene" to describe "factors" located on chromosomes: he observed chromosomal movement during meiosis and developedthe chromosomal theory of heredity

1905-
1908
William Bateson and Reginal Crudell Punnett

demonstrated actions of some genes modify action of other genes: the first time gene regulation was demonstrated

1910
Thomas Hunt Morgan was the first to recognise genes are carried on chromosomes: the basis for modern genetics. He demonstrated the existence of sex-linked genes and expanded trait linkage using "crossing-over"

1911
Alfred Sturtevant, mapped the locations of several fruit fly genes. This was the first genetic map

1926
Thomas Hunt Morgan published the "theory of the gene" based on Mendelian genetics

1933
A new technique, electrophoresis, was introduced by Arne Tiselius for separating proteins in solution

1937
Frederick Charles Bawden discovered tobacco mosaic virus RNA

1944
Barbara McClintock reported transposable elements: "jumping genes"

1946
Edward Tatum and Joshua Lederberg discovered that bacteria can exchange genetic material directly through conjugation Max Delbruck and Alfred Day Hershey discovered a combination of genetic material from viruses: genetic recombination

1950
Erwin Chargaff found that amounts of adenine and thymine and cytosine and guanine in DNA are always about the same. This is now called "Chargaff's Rules"

1952
Rosalind Franklin and Maurice

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