Pancreatic Cancer Hereditary

The major question that many people ask themselves in regard to cancer is, is it hereditary? Could I be more susceptible to the development of cancer based on my family history?
Pancreatic cancer is considered hereditary when a person has certain genetic syndromes. These genetic abnormalities cause as many as 10% of pancreatic cancers. Genetic syndromes that can cause exocrine pancreatic cancer are:
 Hereditary breast and ovarian cancer syndrome
 Familial melanoma
 Familial pancreatitis
 Hereditary non-polyposis colorectal cancer (Lynch syndrome)
 Peutz-Jeghers syndrome (PJS)
 Von Hippel-Lindau syndrome
Pancreatic neuroendocrine tumors and cancers can also be cause by genetic syndromes, such as:
 Neurofibromatosis, type 1
 Multiple
It can be from an atypical number of chromosomes or a structural abnormality in one or more chromosomes. Departures from the normal set of chromosomes can refer to changes in the number of sets of chromosomes (ploidy), changes in the number of individual chromosomes (somy), or changes in appearance of individual chromosomes through mutation-induced rearrangements. They can be associated with genetic diseases or with species differences.

Humans normally have 23 pairs of chromosomes- making 46 in total. One pair are the sex chromosomes- the ova and the sperm each carry 23 chromosomes. The two different types of aberrations are numeric and
The sperm cells from males and the eggs from cells. The cells have an organized nucleus, produces the sex cells which are the male and female gametes. Meiosis is the process where a diploid cell is divided into four daughter cells and is the process that helps with genetic diversity. There is meiosis 1 which is where no chromatids are copied and only one copy is given to each daughter cell and then meiosis 2 the chromatids separate and given to each gamete. During meiosis chromatids may cross over resulting in the recombination of segments causing genetic diversity of genes because they intermix from each parent. Meiosis helps ensure offspring have the correct number of chromosomes contributing to genetic variation. During meiosis, cells are split so that genetic information is divided up into multiple gametes. The genetic information you got from your parents is randomly divided, and this random distribution of paternal and maternal chromosomes is called independent assortment. Meiosis can cause less chromosomes because half of the normal set come from the father and half from the mother which then creates a full diploid cell. These cells are the only cells in the human body only containing half of the