This may help to reduce all symptoms of PCOS and lessen the long-term risk of infertility and type 2 diabetes mellitus. This is the major line of PCOS treatment, such as improved exercise, diet modifications, and weight loss can help to decrease the metabolic irregularities associated with PCOS. Weight loss has been known to correct oligo anovulation and advance the ability of women with PCOS to have successful …show more content…
This type of therapy can be used to control androgen levels and reduce the signs of hyperandrogenism as well as to control menstrual cycles which will also help to diminish the risk of heavy and irregular menstrual bleeding related to the loss of normal estrogen and progesterone levels in the body. Treatment of acne and hirsutism can be successfully done with anti-androgens such as spironolactone, finasteride, and flutamide. Spironolactone and flutamide inhibits dihydrotestosterone and testosterone by binding to their receptors in outer cells such as hair follicles. Finasteride hinders the conversion of testosterone to the more effective dihydrotestosterone in the outer cells.
Treatment of glucose intolerance, hyperinsulinemia, and anovulation can be achieved with Metformin. Decreasing circulating insulin levels may likely reduce ovarian androgen synthesis. Metformin diminishes glucose intolerance and hyperinsulinemia by increasing insulin sensitivity at the insulin target cells and decreasing hepatic gluconeogenesis and lipogenesis. It can also be used to avoid and control type 2 diabetes mellitus. When all these measures are taken, ovulation can be induced