Peroxisome in Animal Cell
| Peroxisome in animal cell | Life sciences, HAN university of applied science, Nijmegen, Netherlands | | Mohsen Ghanbari | 30-12-2012 |
Peroxisome in animal cell
Author: Mohsen Ghanbari
Abstract
Peroxisomes have an essential function in cell metabolism. [1] They are small, membrane bounded organelles that have at least fifty different enzymes for several metabolic reactions. [2] Their appearance is like lysosomes; however, their main function is oxidation reactions especially oxidation of hydrogen peroxide and producing oxygen and water. There are diseases related and caused by this organelle that can be classified in three groups. [2] First group is a disorder duo to overall dysfunction of peroxisomes, like zellweger syndrome, second group duo to dysfunction of only some peroxisomal functions, Example for disorder of this group is rhizomelic chondrodysplasia punctata and third group because of dysfunction of a single peroxisomal function, Example of this group is acatalasemia. In this review I will report the function and dysfunction of peroxisomes, their appearance, related diseases future plans as well as techniques for isolation and visualization of them. From the literature it is known that beta oxidation of long chain and very long chain fatty acids is a lake in group one disorders like infantile refsum's. On the other hand in x-linked adrenoleukodystrophy the lake of beta oxidation of very long chain fatty acids can be seen.
Introduction
Peroxisome is a core shape organelle in both animal and plant cells bounded by a single membrane.[3] The main function is oxidation in other word it contain enzymes that transfer hydrogen from various substrate to oxygen making hydrogen peroxide as a by-product.
The reactions inside peroxisomes have different functions such as: breaking down the fatty acids to smaller molecules for further reactions in mitochondria, detoxifying the harmful compounds in cells especially liver cells. Peroxisomes grow
Peroxisome in animal cell
Author: Mohsen Ghanbari
Abstract
Peroxisomes have an essential function in cell metabolism. [1] They are small, membrane bounded organelles that have at least fifty different enzymes for several metabolic reactions. [2] Their appearance is like lysosomes; however, their main function is oxidation reactions especially oxidation of hydrogen peroxide and producing oxygen and water. There are diseases related and caused by this organelle that can be classified in three groups. [2] First group is a disorder duo to overall dysfunction of peroxisomes, like zellweger syndrome, second group duo to dysfunction of only some peroxisomal functions, Example for disorder of this group is rhizomelic chondrodysplasia punctata and third group because of dysfunction of a single peroxisomal function, Example of this group is acatalasemia. In this review I will report the function and dysfunction of peroxisomes, their appearance, related diseases future plans as well as techniques for isolation and visualization of them. From the literature it is known that beta oxidation of long chain and very long chain fatty acids is a lake in group one disorders like infantile refsum's. On the other hand in x-linked adrenoleukodystrophy the lake of beta oxidation of very long chain fatty acids can be seen.
Introduction
Peroxisome is a core shape organelle in both animal and plant cells bounded by a single membrane.[3] The main function is oxidation in other word it contain enzymes that transfer hydrogen from various substrate to oxygen making hydrogen peroxide as a by-product.
The reactions inside peroxisomes have different functions such as: breaking down the fatty acids to smaller molecules for further reactions in mitochondria, detoxifying the harmful compounds in cells especially liver cells. Peroxisomes grow
References: [3] Neil A. Campbell, Jane B. Reece, Lisa A Urry, Michael L.Cain, Steven A. Wasserman, Peter V. Minorsky et al. Biology. Eighth edition. Pearson international edition. 2008. P.110-111.