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Pinel - Hunger, Eating and Health

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Pinel - Hunger, Eating and Health
Lecture 10a THE DUAL-CENTER SET-POINT MODEL OF EATINGCOURSE MATERIAL AND Pinel LECTURE NOTES
Outline: 1. 2. 3. 4. 5. The Early Studies Glucostatic and Lipostatic Theories v. Positive-Incentive Theories a. Glucostatic and Lipostatic Theories b. Positive-Incentive Theories Hypothalamic Hunger and Satiety Centers and The Dual-Center Set-Point Model a. Ventromedial Hypothalamus b. Lateral Hypothalamus Positive-Incentive Models of Feeding Current Research on the Biopsychology of Eating a. Palatability and Positive Incentives b Energy Expenditure and Body-Fat Homeostasis c. Satiety Peptides d. Reevaluation of the Role of the Ventral Hypothalamus e. Role of Learning in Eating A Settling-Point Model of Body-Weight Regulation

6.

Lecture Notes 1. The Early Studies (use Digital Image Archive Figure CH10F01.BMP)

Energy is available to the body in three forms: (1) lipids (fats), (2) proteins (broken into amino acids), and (3) glucose (simple sugar byproducts of carbohydrates) Energy metabolism occurs in three phases (use Digital Image CH10F03.BMP); open in browser PRO version
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1) the cephalic phase (preparatory), 2) absorptive phase (energy absorbed into the bloodstream), and 3) the fasting phase (body utilizes food stores) The first influential study of the physiological basis of hunger was conducted in 1912 by Canon and Washburn;
Washburn swallowed a balloon on the end of a thin tube, the balloon was partially

inflated, and a pressure gauge was attached to the other end of the tube each time that he had a large stomach contraction, Washburn reported a pang of hunger; this led to the view that stomach contractions are a major factor in hunger. But the finding that animals whose stomachs had been denervated or completely removed ate enough to maintain their body weights discredited this view; in addition, people with no stomachs report feeling hungry and maintain their body weights; they eat

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