It would appear that lupeol shows no toxic effects at reasonable levels in mice. No adverse effects have yet been seen, and research is still at an early stage. We currently have no long term human use studies to base any assumptions on, nevertheless I'm sure we'll start seeing those pretty quickly.
I have to stress that many of the studies on lupeol are conducted either in the lab (in-vitro) or in the murine model (in mice) and don't necceserily mean these effects will be translated into human results. However, the studies are very bullish and the results hugely positive.
Almost all of the studies I have read go on to conclude that lupeol warrents further investigation and mention the very strong possibilities of lupeol
being used in combination therapies for cancer and other diseases.
This may sound dissapointing if you're looking for a quick supplement fix. However, Don't be too disappointed as I'm sure there will be a supplement version along very soon. Furthermore, eating a diet full of the fruits and vegetables on the list below should be a priority for anyone wanting to escape the clutches of disease.
We don't need science to tell us that, or to discover a certain compound before were able to eat it and use it naturally in our bodies. Besides, when we eat that way we also get the benefit of a miriad of other beneficial synergistic compounds that one isolated substance could never give us.
Conclusion
Look out for lupeol making an appearance as one of the next big things. The range of applications and the bullish language it is being described in give me great hope for its future. Let us hope we start to see effective arthritis supplements and treatments made from this safe natural product soon.
Until then...Hit the veggies hard!