Radiotherapy Research Paper
To understand the effects of radiotherapy on the reproductive system, the various organs related to this organ should be considered, as well as, consideration of the gender, age of the person and the amount of radiation exposed.
• Pituitary axis
Illnesses treated with radiation in areas containing the pituitary gland usually have a defect in the pituitary axis. The amount of damage of the total dose may be low as the one used to treat children with acute leukemia (18-40Gy) or many as 60Gy to treat a range of cancers such as pituitary tumors, nose, pharynx, and skull tumors, as well as dose size, Time for treatment. The higher the dose of radiation on the axis of the pituitary gland, the more time needed to adjust pituitary deficiency is the loss of one or more hormones of the pituitary gland, and increased numbers of the hormone imbalance. These hormones come on growth hormone, gonorrhea hormones, follicle stimulating hormone, and luteinizing hormone. In addition to the hormone adrenal peel and thyroid stimulating thyroid gland. Table () shows the effect of different …show more content…
doses on each hormone of the pituitary gland in children. These changes may lead to abnormal growth and early onset in children, and an impact on public health and fertility in adults.
• Radiation therapy and testicular
The testis is one of the most affected by radiation therapy.
Even a few doses (0.15 g) may result in a significant reduction in the amount of sperm. Exposure to large doses (4g) may result in irreversible permanent damage to the testicle. Sperm can live for 46 days and reach ejaculation through EVERNET channels lasting 4-12 days. Therefore, when the patient is exposed to radiation (1.5-2 good) in the days 50-60 the first number of sperm decreased by 50% and continue to increase until reaching the sperm. The sperm cell damage is greater after treatment ends 4-6 months or exposure to high doses of radiation. However, thanks to the regeneration of stem cells that survived after treatment, the semen can return to normal size during 9-18 months for the few doses and 5 years or more for large doses, and to this day scientists have not known the relationship between the radiation dose and the number of
sperm.
• Radiation therapy and ovaries
The natural ovary at birth has approximately 1 million non-renewable primitive bulbs that decrease with age. These follicles are associated with ovarian fertilization, so any deficiency or effect in the follicle leads to an effect in the fertility of the ovary. Cancer radiation therapy depletes the ovary reserve, which reduces ovarian fertility or even menopause completely (infertility) and menopause before the age of 40. Treatment doses that cause infertility in women vary by age. The higher the age of women, the greater the risk of menopause and persistent ovarian failure. According to Wallace et al., The dose (2-4 Gy) of radiotherapy is sufficient to exhaust half of the ovarian reserve in general.
• Pituitary axis
Illnesses treated with radiation in areas containing the pituitary gland usually have a defect in the pituitary axis. The amount of damage of the total dose may be low as the one used to treat children with acute leukemia (18-40Gy) or many as 60Gy to treat a range of cancers such as pituitary tumors, nose, pharynx, and skull tumors, as well as dose size, Time for treatment. The higher the dose of radiation on the axis of the pituitary gland, the more time needed to adjust pituitary deficiency is the loss of one or more hormones of the pituitary gland, and increased numbers of the hormone imbalance. These hormones come on growth hormone, gonorrhea hormones, follicle stimulating hormone, and luteinizing hormone. In addition to the hormone adrenal peel and thyroid stimulating thyroid gland. Table () shows the effect of different …show more content…
doses on each hormone of the pituitary gland in children. These changes may lead to abnormal growth and early onset in children, and an impact on public health and fertility in adults.
• Radiation therapy and testicular
The testis is one of the most affected by radiation therapy.
Even a few doses (0.15 g) may result in a significant reduction in the amount of sperm. Exposure to large doses (4g) may result in irreversible permanent damage to the testicle. Sperm can live for 46 days and reach ejaculation through EVERNET channels lasting 4-12 days. Therefore, when the patient is exposed to radiation (1.5-2 good) in the days 50-60 the first number of sperm decreased by 50% and continue to increase until reaching the sperm. The sperm cell damage is greater after treatment ends 4-6 months or exposure to high doses of radiation. However, thanks to the regeneration of stem cells that survived after treatment, the semen can return to normal size during 9-18 months for the few doses and 5 years or more for large doses, and to this day scientists have not known the relationship between the radiation dose and the number of
sperm.
• Radiation therapy and ovaries
The natural ovary at birth has approximately 1 million non-renewable primitive bulbs that decrease with age. These follicles are associated with ovarian fertilization, so any deficiency or effect in the follicle leads to an effect in the fertility of the ovary. Cancer radiation therapy depletes the ovary reserve, which reduces ovarian fertility or even menopause completely (infertility) and menopause before the age of 40. Treatment doses that cause infertility in women vary by age. The higher the age of women, the greater the risk of menopause and persistent ovarian failure. According to Wallace et al., The dose (2-4 Gy) of radiotherapy is sufficient to exhaust half of the ovarian reserve in general.