1.1 Background information
The term `Malaria ' originates from Medieval Italian Mala aria which mean “bad air”; and the disease was formerly called Ague or Marsh fever due to its association with swamps and marshland, (Watkins, 2001). Scientific studies on Malaria made their first significant advance in 1880, when Charles Louis Alphonse Laveran a French army doctor working in the military hospital of Constantine in Algeria observed malaria plasmodium parasites inside the red blood cell of people suffering from Malaria. Documentation of report on discovery of origin of Malaria, one of the deadliest diseases of humanity shows that Chimpanzees, native to equatorial Africa have been identified as the original source of the parasite that likely moved from them to humans via mosquitoes. Wolfe, (2009) identified several parasites from Chimpanzee that show Malarial jumped from animal to human. Malaria is transmitted by Anopheline mosquitoes the number and type of which determine the extent of transmission in a given area. The plasmodium falciparum accounts for the majority of infections and is most lethal. Transmission is affected by climate and geography and often coincides with the rainy season.
In WHO/UNICEF, (2005) report malaria is one of the most devastating global public health problems with more than one million deaths and approximately 300-500 million cases of malaria annually. WHO, (2010) report, Malaria is by far the world’s worse tropical parasitic disease, and kills more people than any other communicable disease. Several studies observed that malaria kills more than 3,000 children daily and is the single most important factor for mortality among children under the age of five. Additionally, an estimated 25 million pregnant women are at risk of malaria. Malaria is endemic in a total of 101 countries and territories 45 countries in WHO’s African region, 21 in WHO’s American region, 4 in WHO’s European region, 14 in WHO’s Eastern
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