Ruboxistaurin Essay

Since diabetes affect many parts of the body like diabetic kidney disease and heart disease. A new experimental drug has been uncovered. The new drug is called Ruboxistaurin or RBX. Ruboxistaurin is a bisindolymaleimid, it releases a protein called kinase C beta or (PKC-beta). It leads to cell growth, fibrosis, and tissue injury. (McAuley) A study done by Eli Lilly showed that Ruboxistaurin reduced the albuminuria, which is an indicator of diabetic nephropathy, by 24%. Also, a study done over the course of a year showed that a group of patients taking RBX had a stable kidney function and another group of patients taking a placebo experienced significant loss of kidney function. (Lemons, M)

Another advance in diabetes cure is to have an artificial
To recap, diabetes is a disease that occurs when a body’s pancreas fails to produce enough of the hormone insulin. Insulin acts like a judge and internally helps organisms maintain a healthy blood to sugar ratio. When this ratio is off balance, one of two post conditions will occur; hyperglycemia, which is onset by a high blood sugar or hypoglycemia, which is onset by having a low blood sugar. Statistically, 10% of our total population is plagued with this deadly disease, with majority being type 2. Type 2 diabetes in most cases is very preventable but mandates health eating and regular exercising. For those who are unwilling to make this sacrifice, there is an assortment of expensive treatments available for them to use which range from insulin injections to daily pills. On going advancements are still being made, some of which have potential to end diabetes altogether, such as artificial transplants. Until this break through arrives, its our belief that using simple common sense to make healthier choices could drastically eradicate this highly avoidable