Scabies Research Papers

Human scabies, an ectoparasitosis transmitted to humans via direct or indirect skin contact, is caused by Sarcoptes scabiei var. hominis - a mite targeting only human beings. Skin eruption with classical scabies is attributable to both the infestation and a hypersensitivity reaction to the mite.

Scabies is generally a nuisance on account of itching, rash, and its ability to spread easily, although there is a possibility of superinfection (especially with Streptococcus pyogenes). The most common sites of infestation are the fingers and the wrists, but in older individuals the infection may manifest as a diffuse truncal eruption.

Characteristic clinical presentation

Scabies has three basic clinical presentations: classic, crusted, and nodular. Classic scabies is the most common form with notable symptoms of severe pruritus (worse in the evening), irritability, fatigue and, in some patients, fever from aforementioned secondary infections. The classic sign of scabies is the burrow, which is defined as a serpigenous grey line in the skin formed by the digestive secretions from the advancing mite.
This presentation of the disease is described as a psoriasiform dermatitis, frequently associated with hyperkeratotic skin crusts that are limited to the scalp, face, nails or