Sildenafizer Drug Repurpose

What if it’s possible to recycle the drugs and reduce the cost and time of making the new one? How come? Does this mean to reuse it after administration? No, that means to invent new usages for the existing drugs. Drug Repurposing While Pfizer was searching for a treatment of cardiovascular disease in 1986, It tested sildenafil for anti-angina, however, the results were not satisfying, but some patients reported that after administration of this drug they felt penis erection, which directed to the common use of sildenafil in the treatment of erectile dysfunction. Moreover, Sildenafil is additionally approved for treatment of portal hypertension. Accordingly, a possible drug for anti-angina had been used in erectile dysfunction as well as portal hypertension; this is what's called “Drug repurposing”, which
For example, it is reducing the cost and time; as inventing new drug needs tons of studies to increase the affinity and selectivity of these drugs together with the safety through other aspects, which are available for those drugs; consequently no need to reproduce them.
Nevertheless, the discovery of new repurposing drugs is obstructed by the lack of knowledge about diseases; but not only the development of computational methods that are going to make screening for the targets, also the improvement of animal and artificial methods are going to give us a light in the path of drug repurposing. Subsequently, there will be cures for these rare diseases.
As long as combining between the computational knowledge with biological knowledge is going to show the difference in the passage of drug repurposing, I am studying now the Bioinformatics specialization in coursera, along with my 5 years study of the drugs in the school of pharmacy. Honestly, working, one day, in discovering extra repurposed drugs for the rare diseases is igniting my