Stevens Johnson Syndrome Case Studies

Stevens johnson syndrome is a rare, life threatening, and severe blistering mucocutaneous disease, most commonly caused by drugs. Other common trigger is anticonvulsants, antibiotics and mycoplasma pneumonia infection. Disease generally starts with fever, malaise, myalgia, headache, vomiting and prodromal symptoms. Followed by diffuse erythematous maculopapular rashes localised to head, neck, trunk and extremity. Later the rash coalesces and makes develop in bullae which further can lead to detachemet of the epidermis. However skin biopsy is needed to confirm the diagnosis for excluding other cause of bullous disease. There may be involvement of mucosal area as well such as eye, nose and genitalia leading to difficulty in swallowing and micturition.