1) Cholera was first described by Filippo Paccini in 1854, but it was Robert Koch's famous description thirty years later that was finally recognized.
2) Cholera came to Florence in 1854 during the Asiatic Cholera Pandemic of 1846-63.
Notes on Cholera (lenntech.com)
Cholera is an acute, diarrhoeal illness caused by infection of the intestine with the bacterium Vibrio Cholerae.
A person may get cholera by drinking water or eating food contaminated with the cholera bacterium. The disease can spread rapidly in areas with inadequate treatment of sewage and drinking water. The cholera bacterium may also live in the environment in brackish rivers and coastal waters.
Approximately 1 in 20 infected people has severe disease characterized by profuse watery diarrhoea, vomiting and leg cramps. In these people rapid loss of body fluids leads to dehydration and shoal. Without treatment death can occur within hours.
Cholera cases and deaths were officially reported by WHO, in the year 2000, from 27 countries in Africa, 9 countries in Latin America, 13 countries in Asia, 2 countries in Europe, and 4 countries in Oceania. In the same year some 140,000 cases resulting in approximately 5000 deaths were officially notified at WHO. Africa accounted for 87% of these cases. Symptoms of Cholera
The primary symptoms of cholera are profuse diarrhoea and vomiting of clear fluid.[1] These symptoms usually start suddenly, half a day to five days after ingestion of the bacteria.[2] The diarrhoea is frequently described as "rice water" in nature and may have a fishy odour.[1] An untreated person with cholera may produce 10 to 20 litres (3 to 5 US gal) of diarrhoea a day.[1] Severe cholera kills about half of affected individuals.[1] Estimates of the ratio of asymptomatic to symptomatic infections have ranged from 3 to 100.[3] Cholera has been nicknamed the "blue death" because a victim's skin turns bluish-gray from extreme loss of fluids.[4]