The Cause Of Progeri Hutchinson-Gilford Syndrome

Progeria, also known as Hutchinson - Gilford Syndrome is a rare, genetic disease which occurs in an unborn child. It is mainly occurs due to the mutation in LMNA gene. LMNA gene is the gene which synthesizes or encodes mRNA which in turn synthesizes protein, lamin A and lamin C. Scientists are researching for the cause of progeria because knowing its cause can help us to know the cause of aging in a normal people.
It results in a prematurely aging, which is also the meaning of progeria, of a children suffering from disease. Progeria leads to an early death of children, mainly at the age of thirteen or fourteen. Death is mainly due to heart attack or stroke which occurs due to the narrowing of the blood vessel, which is known as vasoconstriction,
or the blockage of blood vessel which decreases or blocks the flow of blood to the heart and brain of the patients.
The children born usually look healthy but the symptoms of progeria starts from the age of two. The symptoms are hair loss, loss of body fat, failure in growth, stiffness of joints, aged – looking skin.